Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death. (Q52723921)

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21 March 2020

title

Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death (English)

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21 March 2020

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21 March 2020

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21 March 2020

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21 March 2020

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21 March 2020

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21 March 2020

Renaud Vandenbosch

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21 March 2020

Florian Jibassia

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21 March 2020

Sébastien Verteneuil

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21 March 2020

Laurent Meijer

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21 March 2020

publication date

16 March 2018

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21 March 2020

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21 March 2020

volume

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21 March 2020

page(s)

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Creative Commons Attribution 4.0 International

21 March 2020

start time

16 March 2018

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April 2022 Public Data File from Crossref

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11 June 2022

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cites work

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Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation

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CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells

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Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models

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Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis

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TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion

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13 August 2018

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10.1038/S41420-018-0044-7

13 August 2018

Identifiers

DOI

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21 March 2020

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21 March 2020

PubMed publication ID

29581894

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