Cysteine protease cathepsins in cardiovascular disease: from basic research to clinical trials. (Q52573372)

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Proteinaceous cysteine protease inhibitors

1 reference

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7 January 2021

The distribution of cathepsin B in human tissues

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Purification and tissue distribution of rat cathepsin L.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization

1 reference

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7 January 2021

Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

1 reference

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7 January 2021

Cathepsin S required for normal MHC class II peptide loading and germinal center development

1 reference

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7 January 2021

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

1 reference

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7 January 2021

Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice

1 reference

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7 January 2021

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

1 reference

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7 January 2021

Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice.

1 reference

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7 January 2021

Regulatory T-cell immunity and its relevance to atherosclerosis

1 reference

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7 January 2021

Experimental myocardial infarction induces altered regulatory T cell hemostasis, and adoptive transfer attenuates subsequent remodeling

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms

1 reference

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7 January 2021

Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implication

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Sickle cell disease activates peripheral blood mononuclear cells to induce cathepsins k and v activity in endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Lysosomal cysteine proteases in atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cysteine protease cathepsin F is expressed in human atherosclerotic lesions, is secreted by cultured macrophages, and modifies low density lipoprotein particles in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Destabilizing role of cathepsin S in murine atherosclerotic plaques

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Characterizing Cathepsin Activity and Macrophage Subtypes in Excised Human Carotid Plaques

1 reference

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7 January 2021

Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Increased serum cathepsin S in patients with atherosclerosis and diabetes

1 reference

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7 January 2021

Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Legumain and cathepsin-L expression in human unstable carotid plaque.

1 reference

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7 January 2021

Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human macrophage foam cells degrade atherosclerotic plaques through cathepsin K mediated processes

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Role of cathepsin K in structural changes in brachiocephalic artery during progression of atherosclerosis in apoE-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice

1 reference

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7 January 2021

Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Pharmacological inhibition of cathepsin S decreases atherosclerotic lesions in Apoe-/- mice

1 reference

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7 January 2021

Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S contributes to macrophage migration via degradation of elastic fibre integrity to facilitate vein graft neointimal hyperplasia.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Selective cathepsin S inhibition attenuates atherosclerosis in apolipoprotein E-deficient mice with chronic renal disease

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Leukocyte cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cysteine protease activity in the wall of abdominal aortic aneurysms

1 reference

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7 January 2021

Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Plasma levels of cathepsins L, K, and V and risks of abdominal aortic aneurysms: a randomized population-based study.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Simultaneous analysis of 1176 gene products in normal human aorta and abdominal aortic aneurysms using a membrane-based complementary DNA expression array

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Genetic linkage of candidate genes in families with abdominal aortic aneurysms?

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K Deficiency Reduces Elastase Perfusion–Induced Abdominal Aortic Aneurysms in Mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Clinical significance of cathepsin L and cathepsin B in dilated cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Increased expression of elastolytic cathepsins S, K, and V and their inhibitor cystatin C in stenotic aortic valves.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances Ang II-induced cardiac inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cell type-specific functions of the lysosomal protease cathepsin L in the heart

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin-L contributes to cardiac repair and remodelling post-infarction

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K knockout alleviates aging-induced cardiac dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Insights into the activation and inhibition of angiotensin II type 1 receptor in the mechanically loaded heart.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human cathepsin X: A cysteine protease with unique carboxypeptidase activity

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Specialized roles for cysteine cathepsins in health and disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

An Active 32-kDa Cathepsin L Is Secreted Directly from HT 1080 Fibrosarcoma Cells and Not via Lysosomal Exocytosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Conformational flexibility and allosteric regulation of cathepsin K.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B activity regulation. Heparin-like glycosaminogylcans protect human cathepsin B from alkaline pH-induced inactivation.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human cathepsin B is a metastable enzyme stabilized by specific ionic interactions associated with the active site

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

cAMP regulates plasma membrane vacuolar-type H+-ATPase assembly and activity in blowfly salivary glands

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe–/– mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Protein Kinase C – Possible Therapeutic Target to Treat Cardiovascular Diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin alphanubeta3

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Dendritic cells in cardiovascular diseases: epiphenomenon, contributor, or therapeutic opportunity

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The role of cathepsin X in cell signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B: association with plasma membrane in metastatic tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Lysosomal cell death at a glance.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

CDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Negative regulation of epidermal growth factor signaling by selective proteolytic mechanisms in the endosome mediated by cathepsin B

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Epidermal growth factor cytoplasmic domain affects ErbB protein degradation by the lysosomal and ubiquitin-proteasome pathway in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Inhibition of cathepsin L-induced degradation of epidermal growth factor receptors by c-Ha-ras gene products

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Key cancer cell signal transduction pathways as therapeutic targets.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B expression in human tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Deficiency of the cysteine protease cathepsin S impairs microvessel growth

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L derived from skeletal muscle cells transfected with bFGF promotes endothelial cell migration

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L is required for endothelial progenitor cell-induced neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Proteolytic degradation of low density lipoproteins by arterial smooth muscle cells: the role of individual cathepsins

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B is a novel gender-dependent determinant of cholesterol absorption from the intestine

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Degradation of apolipoprotein B-100 by lysosomal cysteine cathepsins.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Enzymatically modified LDL induces cathepsin H in human monocytes: potential relevance in early atherogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsins F and S block HDL3-induced cholesterol efflux from macrophage foam cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S expression is up-regulated following balloon angioplasty in the hypercholesterolemic rabbit

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Uptake of Oxidized LDL by Macrophages Results in Partial Lysosomal Enzyme Inactivation and Relocation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S generates soluble CX3CL1 (fractalkine) in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin-regulated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Toxic proteins released from mitochondria in cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B inactivation attenuates the apoptotic injury induced by ischemia/reperfusion of mouse liver

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Potentiation of apoptosis by histone deacetylase inhibitors and doxorubicin combination: cytoplasmic cathepsin B as a mediator of apoptosis in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B is involved in the heat shock induced cardiomyocytes apoptosis as well as the anti-apoptosis effect of HSP-70.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B controls the persistence of memory CD8+ T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: potential role in atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Identification of interleukin-8 converting enzyme as cathepsin L.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Glial uptake of amyloid beta induces NLRP3 inflammasome formation via cathepsin-dependent degradation of NLRP10.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Odanacatib, A Cathepsin K-Specific Inhibitor, Inhibits Inflammation and Bone Loss Caused by Periodontal Diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Monocyte-Macrophages and T Cells in Atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Immune-inflammatory responses in atherosclerosis: Role of an adaptive immunity mainly driven by T and B cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human and mouse proteases: a comparative genomic approach

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin L Inhibition Prevents Murine Autoimmune Diabetes via Suppression of CD8+ T Cell Activity

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Treatment with cathepsin L inhibitor potentiates Th2-type immune response in Leishmania major-infected BALB/c mice

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

B-cell lymphopoiesis is regulated by cathepsin L.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S activity regulates antigen presentation and immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Central and overlapping role of Cathepsin B and inflammasome adaptor ASC in antigen presenting function of human dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Atherosclerosis in rheumatoid arthritis: is it all about inflammation?

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Aortic aneurysms in systemic lupus erythematosus: a meta-analysis of 35 cases in the literature and two different pathogeneses

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Aortic aneurysm associated with rheumatoid arthritis: a population-based cross-sectional study

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Increased prevalence of vulnerable atherosclerotic plaques and low levels of natural IgM antibodies against phosphorylcholine in patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Accelerated atherosclerosis in ApoE deficient lupus mouse models.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Circulating plasma levels of cathepsin S and L are not associated with disease severity in patients with rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Redundancy between Cysteine Cathepsins in Murine Experimental Autoimmune Encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Pathogenetic aspects of systemic lupus erythematosus with an emphasis on regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

TLR7 and TLR9 in SLE: when sensing self goes wrong

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Regulatory T cells and pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Increased Circulating Cathepsin K in Patients with Chronic Heart Failure

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Circulating cathepsin K as a potential novel biomarker of coronary artery disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Levels of cathepsins in acute myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Plasma Cathepsin L and Its Related Pro/Antiangiogenic Factors Play Useful Roles in Predicting Rich Coronary Collaterals in Patients with Coronary Heart Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Impact of circulating cathepsin K on the coronary calcification and the clinical outcome in chronic kidney disease patients

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Combined Cathepsin S and hs-CRP predicting inflammation of abdominal aortic aneurysm

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Association between serum cathepsin S and mortality in older adults

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The association between serum cathepsin L and mortality in older adults

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The Future of Cysteine Cathepsins in Disease Management

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Identification of a potent and selective non-basic cathepsin K inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K inhibitors: a novel target for osteoporosis therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the Long-Term Odanacatib Fracture Trial

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin K inhibitors as treatment of bone metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The consequences of lysosomotropism on the design of selective cathepsin K inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The effect of the cathepsin K inhibitor ONO-5334 on trabecular and cortical bone in postmenopausal osteoporosis: the OCEAN study.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Morning vs evening dosing of the cathepsin K inhibitor ONO-5334: effects on bone resorption in postmenopausal women in a randomized, phase 1 trial

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

An oral cathepsin K inhibitor ONO-5334 inhibits N-terminal and C-terminal collagen crosslinks in serum and urine at similar plasma concentrations in postmenopausal women.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Bone turnover markers and pharmacokinetics of a new sustained-release formulation of the cathepsin K inhibitor, ONO-5334, in healthy post-menopausal women

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Elucidating the inosinome: global approaches to adenosine-to-inosine RNA editing

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Predicting sites of ADAR editing in double-stranded RNA

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Widespread RNA editing of embedded alu elements in the human transcriptome

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Unraveling divergent gene expression profiles in bicuspid and tricuspid aortic valve patients with thoracic aortic dilatation: the ASAP study

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Chondroitin sulfate promotes activation of cathepsin K.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Regulation of collagenase activities of human cathepsins by glycosaminoglycans

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Thyroid functions of mouse cathepsins B, K, and L.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

The collagenolytic activity of cathepsin K is unique among mammalian proteinases

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Procathepsin L degrades extracellular matrix proteins in the presence of glycosaminoglycans in vitro

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

A comparison of four cathepsins (B, L, N and S) with collagenolytic activity from rabbit spleen

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Secreted cathepsin L generates endostatin from collagen XVIII

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cysteine cathepsins S and L modulate anti-angiogenic activities of human endostatin

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Elastin degradation by cathepsin V requires two exosites

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Structural basis for different inhibitory specificities of human cystatins C and D

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Laminar shear stress inhibits cathepsin L activity in endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Amyloid-β increases metallo- and cysteine protease activities in human macrophages.

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

IL-10 synergizes with IL-4 and IL-13 in inhibiting lysosomal enzyme secretion by human monocytes and lamina propria mononuclear cells from patients with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021

Fluid shear-induced cathepsin B release in the control of Mac1-dependent neutrophil adhesion

1 reference

https://api.crossref.org/works/10.1038%2FS41569-018-0002-3

7 January 2021