GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40). (Q51364035)

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scientific article published on 25 October 2016

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English	GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40).	scientific article published on 25 October 2016

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Europe PubMed Central

PubMed publication ID

27779915

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26 March 2020

title

GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40) (English)

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Europe PubMed Central

PubMed publication ID

27779915

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26 March 2020

main subject

triglyceride

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inferred from title

author

Jeppe Pio Ekberg

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1

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Europe PubMed Central

PubMed publication ID

27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

Maria Hauge

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2

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PubMed publication ID

27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

Pascal Timshel

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9

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27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

Thue W Schwartz

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16

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27779915

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26 March 2020

Anna Sofie Husted

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6

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27779915

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26 March 2020

Kristoffer Lihme Egerod

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8

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27779915

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26 March 2020

Fiona Gribble

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11

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27779915

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26 March 2020

Birgitte Holst

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15

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27779915

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26 March 2020

author name string

Line V Kristensen

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3

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27779915

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26 March 2020

Andreas N Madsen

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4

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27779915

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26 March 2020

Maja S Engelstoft

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5

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27779915

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26 March 2020

Rasmus Sichlau

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7

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PubMed publication ID

27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

Timothy J Kowalski

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10

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PubMed publication ID

27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

Frank Reiman

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12

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27779915

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26 March 2020

Harald S Hansen

series ordinal

13

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PubMed publication ID

27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

Andrew D Howard

series ordinal

14

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27779915

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

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26 March 2020

language of work or name

English

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publication date

25 October 2016

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PubMed publication ID

27779915

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26 March 2020

published in

Endocrinology

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PubMed publication ID

27779915

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26 March 2020

volume

157

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27779915

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26 March 2020

issue

12

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27779915

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26 March 2020

page(s)

4561-4569

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27779915

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26 March 2020

cites work

Dietary Lipids Inform the Gut and Brain about Meal Arrival via CD36-Mediated Signal Transduction

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

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Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

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Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

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Effects of JNJ-38431055, a novel GPR119 receptor agonist, in randomized, double-blind, placebo-controlled studies in subjects with type 2 diabetes.

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

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Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

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Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells

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12 December 2020

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

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GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

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inferred from PubMed ID database lookup

GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

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inferred from PubMed ID database lookup

Nutrient sensing in the gut: new roads to therapeutics?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of effects of ingested medium- and long-chain triglyceride on gallbladder volume and release of cholecystokinin and other gut peptides

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid receptor GPR120 is highly expressed in enteroendocrine K cells of the upper small intestine and has a critical role in GIP secretion after fat ingestion

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized, double-blind, dose-ranging study of TAK-875, a novel GPR40 agonist, in Japanese patients with inadequately controlled type 2 diabetes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dietary fat on appetite and energy intake in health and obesity--oral and gastrointestinal sensory contributions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incretin and islet hormonal responses to fat and protein ingestion in healthy men.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal hormonal responses on GPR119 activation in lean and diseased rodent models of type 2 diabetes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPR119 as a fat sensor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose sensing in L cells: a primary cell study

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/27779915

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1210/EN.2016-1334

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stated in

Europe PubMed Central

PubMed publication ID

27779915

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 March 2020

Fatcat ID

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Fatcat

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https://api.fatcat.wiki/v0/release/bmhpe2czkzcj7ikwyk5ssb6tge

retrieved

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

7212052

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Fatcat

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https://api.fatcat.wiki/v0/release/bmhpe2czkzcj7ikwyk5ssb6tge

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24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

27779915

1 reference

stated in

Europe PubMed Central

PubMed publication ID

27779915

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27779915%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 March 2020

 

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