Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage. (Q50663556)

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31 December 2019

title

Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage (English)

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31 December 2019

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Umesh Sharma

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31 December 2019

Nour-Eddine Rhaleb

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Saraswati Pokharel

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Pamela Harding

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31 December 2019

Saman Rasoul

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Hongmei Peng

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Oscar A Carretero

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publication date

4 January 2008

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American Journal of Physiology Heart and Circulatory Physiology

31 December 2019

published in

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volume

294

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issue

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page(s)

H1226-32

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Characterization and localization of Ac-SDKP receptor binding sites using 125I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts

31 December 2019

cites work

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12 December 2020

Decreased endogenous levels of Ac-SDKP promote organ fibrosis

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12 December 2020

Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension

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12 December 2020

Modulating leukocyte recruitment in inflammation

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12 December 2020

In vitro effect of acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) analogs resistant to angiotensin I-converting enzyme on hematopoietic stem cell and progenitor cell proliferation

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12 December 2020

Ac-SDKP reverses cardiac fibrosis in rats with renovascular hypertension

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12 December 2020

Further studies on the biological activities of the CFU-S inhibitory tetrapeptide AcSDKP. I. The precise point of the cell cycle sensitive to AcSDKP. Studies on the effect of AcSDKP on GM-CFC and on the possible involvement of T-lymphocytes in AcSDK

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12 December 2020

Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

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12 December 2020

Protein tyrosine kinase inhibitors inhibit chemotaxis of vascular smooth muscle cells

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12 December 2020

N-acetyl-seryl-aspartyl-lysyl-proline inhibits DNA synthesis in human mesangial cells via up-regulation of cell cycle modulators

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12 December 2020

Direct and reversible inhibitory effect of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Seraspenide) on the growth of human CD34+ subpopulations in response to growth factors

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12 December 2020

Acetyl-seryl-aspartyl-lysyl-proline is a novel natural cell cycle regulator of renal cells

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12 December 2020

Inhibition of human bone marrow progenitors by the synthetic tetrapeptide AcSDKP

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12 December 2020

Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction

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12 December 2020

High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: a new marker of chronic angiotensin-converting enzyme inhibition

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12 December 2020

N-acetyl-seryl-aspartyl-lysyl-proline stimulates angiogenesis in vitro and in vivo.

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12 December 2020

Long-term effect of N-acetyl-seryl-aspartyl-lysyl-proline on left ventricular collagen deposition in rats with 2-kidney, 1-clip hypertension

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12 December 2020

Comparison of the inhibitory effect of AcSDKP, TNF-alpha, TGF-beta, and MIP-1 alpha on marrow-purified CD34+ progenitors

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12 December 2020

Inflammatory mediators and the failing heart: past, present, and the foreseeable future

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12 December 2020

Angiotensin-converting enzyme inhibitors: a new mechanism of action.

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12 December 2020

Captopril inhibits the proliferation of hematopoietic stem and progenitor cells in murine long-term bone marrow cultures

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12 December 2020

Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components

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12 December 2020

The molecular specificity of action of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in the control of hematopoietic stem cell proliferation

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12 December 2020

Reduction of cardiac fibrosis decreases systolic performance without affecting diastolic function in hypertensive rats.

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12 December 2020

N-acetyl-Ser-Asp-Lys-Pro inhibits phosphorylation of Smad2 in cardiac fibroblasts.

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12 December 2020

Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction.

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12 December 2020

The tetrapeptide AcSDKP specifically blocks the cycling of primitive normal but not leukemic progenitors in long-term culture: evidence for an indirect mechanism

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12 December 2020

Reduced macrophage recruitment, proliferation, and activation in colony-stimulating factor-1-deficient mice results in decreased tubular apoptosis during renal inflammation

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12 December 2020

Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts.

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12 December 2020

Hypertension-induced end-organ damage : A new transgenic approach to an old problem

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12 December 2020

SIRIUS RED F3BA AS A STAIN FOR CONNECTIVE TISSUE

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12 December 2020

Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression

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12 December 2020

The tetrapeptide AcSDKP, a negative regulator of cell cycle entry, inhibits the proliferation of human and chicken lymphocytes

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12 December 2020

N-Acetyl-seryl-aspartyl-lysyl-proline inhibits TGF-beta-mediated plasminogen activator inhibitor-1 expression via inhibition of Smad pathway in human mesangial cells

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12 December 2020

BCG-Activated Macrophages: Comparison as Effectors in Direct Tumor-Cell Cytotoxicity and Antibody Dependent Cell-Mediated Cytotoxicity

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12 December 2020

Cardiac overexpression of monocyte chemoattractant protein-1 in transgenic mice prevents cardiac dysfunction and remodeling after myocardial infarction

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12 December 2020

Antifibrotic effect of Ac-SDKP and angiotensin-converting enzyme inhibition in hypertension.

1 reference

12 December 2020

The tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Goralatide) protects from doxorubicin-induced toxicity: improvement in mice survival and protection of bone marrow stem cells and progenitors

1 reference

12 December 2020

Antifibrotic effects of N-acetyl-seryl-aspartyl-Lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats.

1 reference

12 December 2020

Distribution of a negative regulator of haematopoietic stem cell proliferation (AcSDKP) and thymosin beta 4 in mouse tissues

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12 December 2020

Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure

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12 December 2020

10.1152/AJPHEART.00305.2007

Identifiers

DOI

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31 December 2019

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31 December 2019

PubMed publication ID

18178715

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