YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors (Q50577910)

15 March 2018

title

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors (English)

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15 March 2018

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15 March 2018

Markus H Heim

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15 March 2018

Yann Abraham

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Michael T Dill

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Patricia Marti

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15 March 2018

Claudia Stein

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15 March 2018

Tanja Blumer

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15 March 2018

Monika Pikiolek

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15 March 2018

Vanessa Orsini

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15 March 2018

Giorgia Jurisic

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15 March 2018

Philippe Megel

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15 March 2018

Zuzanna Makowska

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15 March 2018

Claudia Agarinis

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15 March 2018

Tewis Bouwmeester

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15 March 2018

Heinz Ruffner

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15 March 2018

Andreas Bauer

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15 March 2018

Christian N Parker

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15 March 2018

Tobias Schmelzle

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15 March 2018

Luigi M Terracciano

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15 March 2018

Jan S Tchorz

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15 March 2018

language of work or name

English

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publication date

14 July 2015

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15 March 2018

published in

Hepatology

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15 March 2018

volume

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15 March 2018

issue

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15 March 2018

page(s)

1497-1510

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15 March 2018

Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

cites work

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Genetic and epigenetic alterations of the INK4a-ARF pathway in cholangiocarcinoma

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Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma

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YAP1 increases organ size and expands undifferentiated progenitor cells

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

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7 January 2021

The Hippo signaling pathway in stem cell biology and cancer

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7 January 2021

TEAD mediates YAP-dependent gene induction and growth control

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7 January 2021

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

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7 January 2021

The TEAD4-YAP/TAZ protein-protein interaction: expected similarities and unexpected differences

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7 January 2021

The Hippo pathway in disease and therapy: cancer and beyond

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7 January 2021

The Hippo pathway and human cancer.

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Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice.

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7 January 2021

YAP activation is an early event and a potential therapeutic target in liver cancer development.

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7 January 2021

Molecular pathways: YAP and TAZ take center stage in organ growth and tumorigenesis.

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7 January 2021

Yap1 acts downstream of α-catenin to control epidermal proliferation

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7 January 2021

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma

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7 January 2021

Yes-associated protein (YAP) functions as a tumor suppressor in breast.

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7 January 2021

Restriction of intestinal stem cell expansion and the regenerative response by YAP.

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Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

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Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation

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7 January 2021

Clinical significance of cell cycle- and apoptosis-related markers in biliary tract cancer: a tissue microarray-based approach revealing a distinctive immunophenotype for intrahepatic and extrahepatic cholangiocarcinomas

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Constitutive Notch2 signaling induces hepatic tumors in mice

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor

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Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output

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Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation

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A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.

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TRAIL and apoptosis induction by TNF-family death receptors.

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7 January 2021

HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.

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7 January 2021

Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors

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7 January 2021

G13 controls angiogenesis through regulation of VEGFR-2 expression

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7 January 2021

Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration

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7 January 2021

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

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7 January 2021

Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage

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7 January 2021

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

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7 January 2021

The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development

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7 January 2021

The hippo tumor suppressor network: from organ size control to stem cells and cancer

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7 January 2021

Hippo pathway activity influences liver cell fate

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7 January 2021

Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes

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7 January 2021

Identifiers

DOI

10.1002/HEP.27992

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15 March 2018

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15 March 2018