Unique Structural and Functional Properties of the ATP-binding Domain of Atypical Protein Kinase C-ι (Q58032683)

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8 November 2019

title

Unique structural and functional properties of the ATP-binding domain of atypical protein kinase C-iota (English)

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8 November 2019

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8 November 2019

A Villunger

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8 November 2019

H Grunicke

series ordinal

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8 November 2019

F Uberall

series ordinal

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8 November 2019

language of work or name

English

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publication date

1 October 2000

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Journal of Biological Chemistry

8 November 2019

published in

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8 November 2019

volume

275

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8 November 2019

issue

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8 November 2019

page(s)

33289-33296

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Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-lambda, epsilon and zeta

8 November 2019

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Protein kinase C zeta isoform is critical for mitogenic signal transduction

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Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein k

21 January 2018

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Conventional PKC-alpha, novel PKC-epsilon and PKC-theta, but not atypical PKC-lambda are MARCKS kinases in intact NIH 3T3 fibroblasts

21 January 2018

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Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.

21 January 2018

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Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific in

21 January 2018

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An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

21 January 2018

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Protein kinase Ciota activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis

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Activation of IkappaB kinase beta by protein kinase C isoforms

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The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

21 January 2018

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Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

21 January 2018

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Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

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Evidence that protein kinase C-alpha activation is a critical event in phorbol ester-induced multiple drug resistance in human colon cancer cells

21 January 2018

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The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

21 January 2018

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Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

21 January 2018

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Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

21 January 2018

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Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

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Crystal structure of cyclin-dependent kinase 2

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Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor

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Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change.

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Structural differences between a ras oncogene protein and the normal protein

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Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src

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Mutational analysis of the nucleotide binding site of the epidermal growth factor receptor and v-Src protein-tyrosine kinases

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Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation

21 January 2018

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Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

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Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: structure-activity analysis and interactions with wortmannin.

21 January 2018

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The CDK-activating kinase (Cak1p) from budding yeast has an unusual ATP-binding pocket

21 January 2018

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Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivo

21 January 2018

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Protein kinase C is regulated in vivo by three functionally distinct phosphorylations

21 January 2018

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Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

21 January 2018

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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

21 January 2018

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Atypical Protein Kinase C ι Protects Human Leukemia Cells against Drug-induced Apoptosis

21 January 2018

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

21 January 2018

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Activation of protein kinase C triggers its ubiquitination and degradation

21 January 2018

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Unique phosphorylation of protein kinase C-alpha in PC12 cells induces resistance to translocation and down-regulation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M002742200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906326%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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