Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke (Q57689686)

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scientific article published on 21 April 2017

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English	Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke	scientific article published on 21 April 2017

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Europe PubMed Central

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6478181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 March 2020

meta-analysis

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title

Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke (English)

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Europe PubMed Central

PMC publication ID

6478181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

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18 March 2020

author

Kailash Krishnan

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2

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Europe PubMed Central

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6478181

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18 March 2020

author name string

Philip Mw Bath

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1

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Europe PubMed Central

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6478181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

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18 March 2020

Jason P Appleton

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3

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Europe PubMed Central

PMC publication ID

6478181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

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18 March 2020

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English

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publication date

21 April 2017

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Europe PubMed Central

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6478181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

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18 March 2020

published in

Cochrane Database of Systematic Reviews

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stated in

Europe PubMed Central

PMC publication ID

6478181

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

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18 March 2020

volume

4

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Europe PubMed Central

PMC publication ID

6478181

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18 March 2020

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CD000398

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Europe PubMed Central

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6478181

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18 March 2020

cites work

Effect of inhibition of nitric oxide synthase on dynamic cerebral autoregulation in humans

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Time course of expression of three nitric oxide synthase isoforms after transient middle cerebral artery occlusion in rats

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The effect of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure and platelet function in acute stroke

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Blood pressure and clinical outcomes in the International Stroke Trial

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L-Arginine increases ischemic injury in wild-type mice but not in iNOS-deficient mice

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

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Role of nitric oxide in the regulation of cerebral blood flow in humans: chemoregulation versus mechanoregulation

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https://pubmed.ncbi.nlm.nih.gov/28429459

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inferred from PubMed ID database lookup

L-arginine dilates rat pial arterioles by nitric oxide-dependent mechanisms and increases blood flow during focal cerebral ischaemia

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12 December 2020

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Nitric oxide-induced blockade of NMDA receptors

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12 December 2020

based on heuristic

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Complications of acute stroke

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

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Calmodulin is a subunit of nitric oxide synthase from macrophages

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12 December 2020

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A SELF-RATING DEPRESSION SCALE

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PubMed

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12 December 2020

based on heuristic

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L-arginine decreases infarct size caused by middle cerebral arterial occlusion in SHR

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

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High blood pressure in acute stroke and subsequent outcome: a systematic review

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12 December 2020

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Targeting eNOS for stroke protection

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal nitric oxide synthase and ischemia-induced neurogenesis

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

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A systematic review of nitric oxide donors and L-arginine in experimental stroke; effects on infarct size and cerebral blood flow.

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PubMed

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12 December 2020

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Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transdermal glyceryl trinitrate lowers blood pressure and maintains cerebral blood flow in recent stroke

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of inducible nitric oxide synthase and cell proliferation in rat brain after transient middle cerebral artery occlusion.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

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Relationship between outcome and baseline blood pressure and other haemodynamic measures in acute ischaemic stroke: data from the TAIST trial

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Can We Improve the Statistical Analysis of Stroke Trials?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma nitric oxide (nitrate/nitrite) levels in acute stroke and their relationship with severity and outcome

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of transdermal glyceryl trinitrate, a nitric oxide donor, on blood pressure, cerebral and cardiac hemodynamics, and plasma nitric oxide levels in acute stroke

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase appears and is co-expressed with the neuronal isoform in interneurons of the rat hippocampus after transient ischemia induced by middle cerebral artery occlusion

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide and prostacyclin. Divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hypertensive response in patients with stroke: pathophysiology and management

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glyceryl trinitrate vs. control, and continuing vs. stopping temporarily prior antihypertensive therapy, in acute stroke: rationale and design of the Efficacy of Nitric Oxide in Stroke (ENOS) trial (ISRCTN99414122).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective randomized comparison of safety and efficacy of nicardipine and nitroprusside drip for control of hypertension in the neurosurgical intensive care unit

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of endothelial nitric oxide synthetase in arteriogenesis after stroke in mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter comparison of outcomes associated with intravenous nitroprusside and nicardipine treatment among patients with intracerebral hemorrhage

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood pressure as a prognostic factor after acute stroke

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion of the National Institutes of Health Stroke Scale and Scandinavian Stroke Scale in acute stroke

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renin-angiotensin system blockade safely reduces blood pressure in patients with minor ischemic stroke during the acute phase

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood Pressure Control in Acute Cerebrovascular Disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-arterial vasodilator use during endovascular therapy for acute ischemic stroke might improve reperfusion rate.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determining the Feasibility of Ambulance-Based Randomised Controlled Trials in Patients with Ultra-Acute Stroke: Study Protocol for the "Rapid Intervention with GTN in Hypertensive Stroke Trial" (RIGHT, ISRCTN66434824)

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility of an ambulance-based stroke trial, and safety of glyceryl trinitrate in ultra-acute stroke: the rapid intervention with glyceryl trinitrate in Hypertensive Stroke Trial (RIGHT, ISRCTN66434824).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organised inpatient (stroke unit) care for stroke

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical analysis plan for the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral antiplatelet therapy for acute ischaemic stroke

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Views of paramedics on their role in an out-of-hospital ambulance-based trial in ultra-acute stroke: qualitative data from the Rapid Intervention With Glyceryl Trinitrate in Hypertensive Stroke Trial (RIGHT).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perioperative antihypertensive treatment in patients of spontaneous intracerebral hemorrhage (PATICH): a clinical trial protocol

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baseline characteristics of the 4011 patients recruited into the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative systolic blood pressure reduction and clinical outcomes in hyperacute intracerebral hemorrhage: the SAMURAI-ICH observational study

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Treatment Delay, Stroke Type, and Thrombolysis on the Effect of Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome after Acute Stroke: A Systematic Review and Meta-Analysis of Individual Patient from Randomised Trials

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and role of guanylate cyclase-cyclic GMP in vascular relaxation.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial cells synthesize nitric oxide from L-arginine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood pressure course in patients with acute stroke and matched controls

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis in clinical trials

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue plasminogen activator for acute ischemic stroke

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide production during focal cerebral ischemia in rats

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gases as biological messengers: nitric oxide and carbon monoxide in the brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is nitric oxide really important for regulation of the cerebral circulation? Yes or no?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal nitric oxide synthase mutant mice show smaller infarcts and attenuated apparent diffusion coefficient changes in the peri-infarct zone during focal cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene

1 reference

stated in

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reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hypertension promotes hemorrhagic transformation in a rabbit embolic stroke model: effect of labetalol

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide plasma levels in patients with chronic and acute cerebrovascular disorders

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiological assessment of nitric oxide (given as sodium nitroprusside) in acute ischaemic stroke

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28429459

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/14651858.CD000398.PUB2

1 reference

stated in

Europe PubMed Central

PMC publication ID

6478181

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 March 2020

PMC publication ID

6478181

1 reference

stated in

Europe PubMed Central

PMC publication ID

6478181

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 March 2020

PubMed publication ID

28429459

1 reference

stated in

Europe PubMed Central

PMC publication ID

6478181

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28429459%20AND%20SRC:MED&resulttype=core&format=json

retrieved

18 March 2020

 

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