IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors (Q57138348)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

title

IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

0 references

1 reference

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26 April 2020

1 reference

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26 April 2020

1 reference

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26 April 2020

1 reference

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26 April 2020

1 reference

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26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Sahil Gupta

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Beatrice Pflüger-Müller

1 reference

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26 April 2020

Ralf P Brandes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Bernhard Brüne

1 reference

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26 April 2020

Dmitry Namgaladze

1 reference

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26 April 2020

language of work or name

English

0 references

publication date

30 July 2018

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26 April 2020

1 reference

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26 April 2020

volume

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26 April 2020

issue

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26 April 2020

page(s)

e1494110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

Immune checkpoint inhibition: prospects for prevention and therapy of hepatocellular carcinoma.

26 April 2020

cites work

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2 November 2018

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Identification and Validation of a PD-L1 Binding Peptide for Determination of PDL1 Expression in Tumors.

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Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade

2 November 2018

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Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.

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2 November 2018

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2 November 2018

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2 November 2018

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IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition.

2 November 2018

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Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk

2 November 2018

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STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation

2 November 2018

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BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression.

2 November 2018

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Differential gene expression in human, murine, and cell line-derived macrophages upon polarization

2 November 2018

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Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages

2 November 2018

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Batf is important for IL-4 expression in T follicular helper cells

2 November 2018

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Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

2 November 2018

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Autocrine amplification of immature myeloid cells by IL-6 in multiple myeloma-infiltrated bone marrow

2 November 2018

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IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer.

2 November 2018

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Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer.

2 November 2018

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STAT3 acts through pre-existing nucleosome-depleted regions bound by FOS during an epigenetic switch linking inflammation to cancer

2 November 2018

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Versatile functions for IL-6 in metabolism and cancer

2 November 2018

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2 November 2018

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2 November 2018

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Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells

2 November 2018

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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

2 November 2018

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Regulation of tumor metastasis by myeloid-derived suppressor cells

2 November 2018

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uPAR induces expression of transforming growth factor β and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.

2 November 2018

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2 November 2018

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The tumor microenvironment is the main source of IL-6 for plasma cell tumor development in mice

2 November 2018

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SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity

2 November 2018

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A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis

2 November 2018

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The tumor microenvironment shapes lineage, transcriptional, and functional diversity of infiltrating myeloid cells

2 November 2018

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2 November 2018

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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

2 November 2018

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The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

2 November 2018

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2 November 2018

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Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients

2 November 2018

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2 November 2018

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JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

2 November 2018

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Distinct properties of cell-type-specific and shared transcription factor binding sites

2 November 2018

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Human effector T cells derived from central memory cells rather than CD8(+)T cells modified by tumor-specific TCR gene transfer possess superior traits for adoptive immunotherapy

2 November 2018

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Macrophage regulation of tumor responses to anticancer therapies

2 November 2018

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Distinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions

2 November 2018

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Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

2 November 2018

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2 November 2018

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Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment.

2 November 2018

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Full-length transcriptome assembly from RNA-Seq data without a reference genome

2 November 2018

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CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3

2 November 2018

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2 November 2018

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Macrophage diversity enhances tumor progression and metastasis

2 November 2018

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IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

2 November 2018

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PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium

2 November 2018

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STATs in cancer inflammation and immunity: a leading role for STAT3

2 November 2018

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Gene expression profiling of the tumor microenvironment during breast cancer progression

2 November 2018

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Identification of interleukin-1 and interleukin-6-responsive genes in human monocyte-derived macrophages using microarrays.

2 November 2018

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Stromal gene expression predicts clinical outcome in breast cancer

2 November 2018

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Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.

2 November 2018

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Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

2 November 2018

1 reference

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PANTHER: a library of protein families and subfamilies indexed by function

2 November 2018

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Partners in crime: VEGF and IL-4 conscript tumour-promoting macrophages

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30288360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dual Faces of IFNγ in Cancer Progression: A Role of PD-L1 Induction in the Determination of Pro- and Antitumor Immunity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30288360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/2162402X.2018.1494110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

PubMed publication ID

30288360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30288360%20AND%20SRC:MED&resulttype=core&format=json