Screening for genes that regulate the differentiation of human megakaryocytic lineage cells (Q57050184)

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article published in the Proceedings of the National Academy of Sciences of the United States of America

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English	Screening for genes that regulate the differentiation of human megakaryocytic lineage cells	article published in the Proceedings of the National Academy of Sciences of the United States of America

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scholarly article

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

title

Screening for genes that regulate the differentiation of human megakaryocytic lineage cells (English)

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stated in

Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

author

Irving Weissman

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6

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Irving L Weissman

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

author name string

Fangfang Zhu

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1

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

Mingye Feng

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2

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PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

Rahul Sinha

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3

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PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

Jun Seita

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4

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

Yasuo Mori

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5

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

language of work or name

English

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publication date

27 August 2018

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Europe PubMed Central

PMC publication ID

6176640

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 April 2020

published in

Proceedings of the National Academy of Sciences of the United States of America

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stated in

Europe PubMed Central

PMC publication ID

6176640

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 April 2020

volume

115

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 April 2020

issue

40

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Europe PubMed Central

PMC publication ID

6176640

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

page(s)

E9308-E9316

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Europe PubMed Central

PMC publication ID

6176640

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

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20 April 2020

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Cloning and characterization of cyclophilin C-associated protein: a candidate natural cellular ligand for cyclophilin C

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Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype.

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PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors

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HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells

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Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors

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FLI-1 is a suppressor of erythroid differentiation in human hematopoietic cells

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Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny.

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Ex vivo expanded peripheral blood progenitor cells provide rapid neutrophil recovery after high-dose chemotherapy in patients with breast cancer

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Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.

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Characterization of mouse clonogenic megakaryocyte progenitors

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Ets-dependent regulation of target gene expression during megakaryopoiesis

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Multilineage transcriptional priming and determination of alternate hematopoietic cell fates

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Early decisions in lymphoid development

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https://pubmed.ncbi.nlm.nih.gov/30150396

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Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

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12 December 2020

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Hematopoiesis: an evolving paradigm for stem cell biology

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A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis.

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A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates

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Gene regulatory networks governing haematopoietic stem cell development and identity

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Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.

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Hematopoietic stem cell: self-renewal versus differentiation

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Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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Transcription factor networks in erythroid cell and megakaryocyte development

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PubMed

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Gene Expression Commons: an open platform for absolute gene expression profiling

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Multiplex genome engineering using CRISPR/Cas systems

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30150396

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA-guided human genome engineering via Cas9

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The calcineurin-NFAT pathway negatively regulates megakaryopoiesis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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12 December 2020

based on heuristic

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Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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12 December 2020

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Repurposing CRISPR/Cas9 for in situ functional assays.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30150396

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic screens in human cells using the CRISPR-Cas9 system

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PubMed

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12 December 2020

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inferred from PubMed ID database lookup

Genome-scale CRISPR-Cas9 knockout screening in human cells

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Epigenetic reprogramming induces the expansion of cord blood stem cells

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Targeted genome editing in human repopulating haematopoietic stem cells

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PubMed

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Improved vectors and genome-wide libraries for CRISPR screening

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PubMed

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Identification and specification of the mouse skeletal stem cell

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Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

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Double trouble: Cyclosporine-induced thrombocytosis in a patient with methotrexate toxicity: Are they related?

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Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets

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Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche

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Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

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reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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12 December 2020

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inferred from PubMed ID database lookup

Identification of human erythroid lineage-committed progenitors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

retrieved

12 December 2020

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Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

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reference URL

https://pubmed.ncbi.nlm.nih.gov/30150396

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Identifiers

DOI

10.1073/PNAS.1805434115

1 reference

stated in

Europe PubMed Central

PMC publication ID

6176640

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 April 2020

PMC publication ID

6176640

1 reference

stated in

Europe PubMed Central

PMC publication ID

6176640

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 April 2020

PubMed publication ID

30150396

1 reference

stated in

Europe PubMed Central

PMC publication ID

6176640

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30150396%20AND%20SRC:MED&resulttype=core&format=json

retrieved

20 April 2020

 

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