Is CTLA-4 a negative regulator for T-cell activation? (Q56908067)

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8 November 2019

title

Is CTLA-4 a negative regulator for T-cell activation? (English)

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8 November 2019

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1 December 2024

lymphocyte activation

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1 December 2024

Y. Liu

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1 December 2024

language of work or name

English

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publication date

1 December 1997

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8 November 2019

December 1997

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9425733

full work available at URL

1 December 2024

https://doi.org/10.1016/s0167-5699(97)01170-5

online access status

open access

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https://api.elsevier.com/content/article/PII:S0167569997011705?httpAccept=text/xml

1 December 2024

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10.1016/S0167-5699(97)01170-5

DOI

https://api.crossref.org/works/10.1016/S0167-5699(97)01170-5

https://api.elsevier.com/content/article/PII:S0167569997011705?httpAccept=text/plain

1 December 2024

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10.1016/S0167-5699(97)01170-5

DOI

https://api.crossref.org/works/10.1016/S0167-5699(97)01170-5

1 December 2024

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8 November 2019

volume

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8 November 2019

issue

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8 November 2019

page(s)

569-572

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A new member of the immunoglobulin superfamily--CTLA-4

8 November 2019

cites work

1 reference

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7 January 2021

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

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7 January 2021

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

1 reference

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7 January 2021

Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

1 reference

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7 January 2021

The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells

1 reference

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7 January 2021

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901170-5

7 January 2021

CTLA-4 can function as a negative regulator of T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901170-5

7 January 2021

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

1 reference

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7 January 2021

The Yin and Yang of T cell costimulation

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7 January 2021

New perspectives of CD28-B7-mediated T cell costimulation

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7 January 2021

Releasing the brakes on antitumor immune response

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7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

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7 January 2021

A novel receptor involved in T-cell activation

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7 January 2021

Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity

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7 January 2021

Dimerization of cell surface receptors in signal transduction

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7 January 2021

Regulation of signal transduction and signal diversity by receptor oligomerization

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7 January 2021

The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction

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7 January 2021

Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice

1 reference

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7 January 2021

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

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7 January 2021

The molecular jury: deciding whether immature thymocytes should live or die.

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7 January 2021

Positive selection of thymocytes

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7 January 2021

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals

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7 January 2021

Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2

1 reference

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7 January 2021

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

1 reference

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7 January 2021

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

1 reference

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7 January 2021

CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion

1 reference

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7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

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7 January 2021

Differential T cell costimulatory requirements in CD28-deficient mice

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7 January 2021

Duration of TCR stimulation determines costimulatory requirement of T cells

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7 January 2021

Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T lymphocytes

1 reference

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7 January 2021

Identification of a costimulatory molecule rapidly induced by CD40L as CD44H.

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7 January 2021

Costimulation of T-cell growth

1 reference

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7 January 2021

Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

1 reference

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7 January 2021

10.1016/S0167-5699(97)01170-5

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9425733%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9425733%20AND%20SRC:MED&resulttype=core&format=json