Review of the neurological benefits of phytocannabinoids. (Q55439675)

10 July 2018

title

Review of the neurological benefits of phytocannabinoids. (English)

1 reference

10 July 2018

author name string

Joseph Maroon

series ordinal

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10 July 2018

Jeff Bost

series ordinal

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10 July 2018

language of work or name

English

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publication date

26 April 2018

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10 July 2018

Surgical Neurology International

published in

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10 July 2018

volume

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10 July 2018

page(s)

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10 July 2018

An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies

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Molecular Targets of Cannabidiol in Neurological Disorders

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Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review

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Δ9-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption

15 July 2018

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Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma

15 July 2018

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Therapeutic modalities for treatment resistant depression: focus on vagal nerve stimulation and ketamine

15 July 2018

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Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

15 July 2018

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An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice

15 July 2018

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Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders: report of the Guideline Development Subcommittee of the American Academy of Neurology

15 July 2018

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15 July 2018

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Cannabidiol in humans-the quest for therapeutic targets

15 July 2018

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Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signaling

15 July 2018

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Neuronal network plasticity and recovery from depression

15 July 2018

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Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory

15 July 2018

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Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

15 July 2018

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Sativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington's disease: role of CB1 and CB2 receptors.

15 July 2018

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Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

15 July 2018

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Cannabinoid facilitation of fear extinction memory recall in humans

15 July 2018

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Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress

15 July 2018

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Potential protective effects of cannabidiol on neuroanatomical alterations in cannabis users and psychosis: a critical review

15 July 2018

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Cannabidiol inhibits angiogenesis by multiple mechanisms

15 July 2018

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Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms

15 July 2018

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On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment

15 July 2018

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Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures

15 July 2018

1 reference

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Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement

15 July 2018

1 reference

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Safety and side effects of cannabidiol, a Cannabis sativa constituent

15 July 2018

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Phytocannabinoids as novel therapeutic agents in CNS disorders.

15 July 2018

1 reference

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Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm

15 July 2018

1 reference

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Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells

15 July 2018

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Prospects for cannabinoid therapies in basal ganglia disorders

15 July 2018

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Insights into pathophysiology and therapy from a mouse model of Dravet syndrome

15 July 2018

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Endocannabinoids and traumatic brain injury

15 July 2018

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Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients

15 July 2018

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The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration

15 July 2018

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Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis

15 July 2018

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Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo

15 July 2018

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Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

15 July 2018

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Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

15 July 2018

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Cannabidiol: a promising drug for neurodegenerative disorders?

15 July 2018

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Emerging strategies for exploiting cannabinoid receptor agonists as medicines

15 July 2018

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Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing

15 July 2018

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Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.

15 July 2018

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Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial

15 July 2018

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Novel cannabinoid receptors

15 July 2018

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Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate

15 July 2018

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The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin

15 July 2018

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Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex

15 July 2018

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Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression

15 July 2018

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Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain

15 July 2018

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Immune tolerance and control of CNS autoimmunity: from animal models to MS patients

15 July 2018

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Endocannabinoids block status epilepticus in cultured hippocampal neurons.

15 July 2018

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The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells

15 July 2018

1 reference

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CB1 receptor selective activation inhibits beta-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons.

15 July 2018

1 reference

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Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes.

15 July 2018

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Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

15 July 2018

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A review of the evidence for efficacy of complementary and alternative medicines in MS

15 July 2018

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The emerging role of the endocannabinoid system in endocrine regulation and energy balance

15 July 2018

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Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up.

15 July 2018

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Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis

15 July 2018

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Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

15 July 2018

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Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients

15 July 2018

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Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons

15 July 2018

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Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

15 July 2018

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Effects of cannabidiol (CBD) on regional cerebral blood flow

15 July 2018

1 reference

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Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis

15 July 2018

1 reference

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Role of endogenous cannabinoids in synaptic signaling

15 July 2018

1 reference

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International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

15 July 2018

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Neurobiology of depression

15 July 2018

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Guidelines for prescribing medical marijuana

15 July 2018

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Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture.

15 July 2018

1 reference

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Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

15 July 2018

1 reference

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Biosynthesis of cannabinoids. Incorporation experiments with (13)C-labeled glucoses

15 July 2018

1 reference

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Endocannabinoids and vascular function.

15 July 2018

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Cannabinoids control spasticity and tremor in a multiple sclerosis model

15 July 2018

1 reference

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The use of cannabis as a mood stabilizer in bipolar disorder: anecdotal evidence and the need for clinical research

15 July 2018

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Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

15 July 2018

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Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain

15 July 2018

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Pharmacology of cannabinoid CB1 and CB2 receptors.

15 July 2018

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The Perceived Effects of Smoked Cannabis on Patients with Multiple Sclerosis

15 July 2018

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Hashish. I. The structure of cannabidiol

15 July 2018

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Open label evaluation of cannabidiol in dystonic movement disorders

15 July 2018

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Prolonged CNS hyperexcitability in mice after a single exposure to delta-9-tetrahydrocannabinol

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Controlled clinical trial of cannabidiol in Huntington's disease

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Brain-derived neurotrophic factor serum levels in heroin-dependent patients after 26weeks of withdrawal

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Preliminary, open-label, pilot study of add-on oral Δ9-tetrahydrocannabinol in chronic post-traumatic stress disorder

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Cannabidiol induces intracellular calcium elevation and cytotoxicity in oligodendrocytes

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Delta 9-tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Effect of cannabinoids on platelet serotonin uptake

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Induction of striatal long-term synaptic depression by moderate frequency activation of cortical afferents in rat.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Immunohistochemical localization of the neural cannabinoid receptor in rat brain

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Hallucinogens of Plant Origin

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS)

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5938896

Stereospecific synthesis of (-)-.DELTA.1- and (-)-.DELTA.1(6)-tetrahydrocannabinols

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29770251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29770251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chronic administration of cannabidiol to healthy volunteers and epileptic patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29770251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4103/SNI.SNI_45_18

1 reference

10 July 2018

PMC publication ID

5938896

1 reference

10 July 2018

PubMed publication ID

29770251

1 reference

10 July 2018