CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease. (Q54957718)

13 June 2018

title

CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease. (English)

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13 June 2018

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Bradley T Hyman

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13 June 2018

Martin Ingelsson

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13 June 2018

Xandra O. Breakefield

Xandra O Breakefield

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13 June 2018

Lars Lannfelt

Lars Lannfelt

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13 June 2018

Vilmantas Giedraitis

Vilmantas Giedraitis

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13 June 2018

J. Keith Joung

J Keith Joung

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13 June 2018

Mikołaj P Zaborowski

Mikołaj P Zaborowski

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13 June 2018

author name string

Bence György

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13 June 2018

Camilla Lööv

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13 June 2018

Shuko Takeda

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13 June 2018

Benjamin P Kleinstiver

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13 June 2018

Caitlin Commins

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13 June 2018

Ksenia Kastanenka

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13 June 2018

Dakai Mu

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13 June 2018

Adrienn Volak

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13 June 2018

Casey A Maguire

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13 June 2018

publication date

16 March 2018

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13 June 2018

Molecular Therapy. Nucleic acids

published in

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13 June 2018

volume

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13 June 2018

page(s)

429-440

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13 June 2018

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

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APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

16 June 2018

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16 June 2018

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Increased beta-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation.

16 June 2018

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16 June 2018

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CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease

16 June 2018

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13 August 2018

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13 August 2018

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13 August 2018

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The genetics of Alzheimer's disease

29 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29858078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Exosome-associated AAV vector as a robust and convenient neuroscience tool

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29858078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.OMTN.2018.03.007

1 reference

13 June 2018

PMC publication ID

5992788

1 reference

13 June 2018

PubMed publication ID

29858078

1 reference

13 June 2018