Apelin activates the expression of inflammatory cytokines in microglial BV2 cells via PI-3K/Akt and MEK/Erk pathways. (Q54072521)

24 May 2018

title

Apelin activates the expression of inflammatory cytokines in microglial BV2 cells via PI-3K/Akt and MEK/Erk pathways. (English)

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24 May 2018

0 references

1 reference

Li Chen

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24 May 2018

Yong Tao

series ordinal

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24 May 2018

YanRong Jiang

series ordinal

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24 May 2018

publication date

8 May 2015

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24 May 2018

Science in China. Series C: Life Sciences

published in

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24 May 2018

volume

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24 May 2018

issue

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24 May 2018

page(s)

531-540

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24 May 2018

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

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Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo

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Apelin is a novel angiogenic factor in retinal endothelial cells

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Apelin is a crucial factor for hypoxia-induced retinal angiogenesis

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Retardation of retinal vascular development in apelin-deficient mice

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Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system

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Apelin in plasma and vitreous and in fibrovascular retinal membranes of patients with proliferative diabetic retinopathy

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Involvement of a Stat3 binding site in inflammation-induced enteric apelin expression

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Microglia in the healthy and degenerating retina: insights from novel mouse models

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The multifaceted profile of activated microglia.

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Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy

21 January 2018

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Microglial activation in human diabetic retinopathy

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Regulatory mechanisms of mitogen-activated kinase signaling

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TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity

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Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia

21 January 2018

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Apelin in epiretinal fibrovascular membranes of patients with retinopathy of prematurity and the changes after intravitreal bevacizumab

21 January 2018

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The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

21 January 2018

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Molecular properties of apelin: tissue distribution and receptor binding

21 January 2018

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Apelin ameliorates TNF-α-induced reduction of glycogen synthesis in the hepatocytes through G protein-coupled receptor APJ.

21 January 2018

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Amino acid sequence and embryonic expression of msr/apj, the mouse homolog of Xenopus X-msr and human APJ

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Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

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IL-1-regulated responses in astrocytes: relevance to injury and recovery

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Apelin-13 regulates proliferation, migration and survival of retinal Müller cells under hypoxia

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Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy.

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The role of inflammatory cytokines in diabetic nephropathy.

21 January 2018

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TNFalpha up-regulates apelin expression in human and mouse adipose tissue.

21 January 2018

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Cilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and inhibiting mitogen-activated protein kinases.

21 January 2018

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21 January 2018

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Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

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The phosphoinositide 3-kinase pathway

21 January 2018

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21 January 2018

Phosphoinositide kinases

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

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Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

21 January 2018

1 reference

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10.1007/S11427-015-4861-0

21 January 2018

Identifiers

DOI

1 reference

24 May 2018

1 reference

24 May 2018