FRA3B and other common fragile sites: the weakest links (Q43922549)

28 November 2017

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title

FRA3B and other common fragile sites: the weakest links (English)

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28 November 2017

C M Croce

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28 November 2017

K Huebner

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28 November 2017

language of work or name

English

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publication date

1 December 2001

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28 November 2017

published in

Nature Reviews Cancer

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28 November 2017

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28 November 2017

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28 November 2017

page(s)

214-221

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Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation

28 November 2017

cites work

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DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

21 January 2018

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Constitutive fragile sites and cancer.

21 January 2018

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The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers

21 January 2018

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Replacement of Fhit in cancer cells suppresses tumorigenicity

21 January 2018

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The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control

21 January 2018

1 reference

Fragile and unstable chromosomes in cancer: causes and consequences

21 January 2018

1 reference

Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites

21 January 2018

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A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs

21 January 2018

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Sequence of the FRA3B common fragile region: Implications for the mechanism of FHIT deletion

21 January 2018

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Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.

21 January 2018

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Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

21 January 2018

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Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2

21 January 2018

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Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

21 January 2018

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Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit

21 January 2018

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Chromosome translocations: dangerous liaisons revisited.

21 January 2018

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

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Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma

21 January 2018

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The FHIT gene 3p14.2 is abnormal in lung cancer.

21 January 2018

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Protein expression and functional analysis of the FHIT gene in human tumor cells

21 January 2018

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Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells

21 January 2018

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Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase

21 January 2018

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Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit

21 January 2018

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Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans

21 January 2018

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Muir-Torre-like syndrome in Fhit-deficient mice

21 January 2018

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The tumor spectrum in FHIT-deficient mice

21 January 2018

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

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Increasing incidence of both major histological types of esophageal carcinomas among men in Sweden

21 January 2018

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FHIT gene therapy prevents tumor development in Fhit-deficient mice.

21 January 2018

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Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability

21 January 2018

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Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines

21 January 2018

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Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity

21 January 2018

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WWOX: a candidate tumor suppressor gene involved in multiple tumor types

21 January 2018

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Molecular Damage in the Bronchial Epithelium of Current and Former Smokers

21 January 2018

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Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector

21 January 2018

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The Characterization of the Common Fragile Site FRA16D and Its Involvement in Multiple Myeloma Translocations

21 January 2018

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Role of FHIT in human cancer

21 January 2018

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7 January 2021

Effect of radiation and cigarette smoking on expression of FUdR-inducible common fragile sites in human peripheral lymphocytes

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7 January 2021

Determination of the specificity of aphidicolin-induced breakage of the human 3p14.2 fragile site

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7 January 2021

Frequent deletions within FRA7G at 7q31.2 in invasive epithelial ovarian cancer

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7 January 2021

Molecular characterization of FRAXB and comparative common fragile site instability in cancer cells

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7 January 2021

Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction

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7 January 2021

Clinical and genetic studies of renal cell carcinomas in a family with a constitutional chromosome 3;8 translocation. Genetics of familial renal carcinoma

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7 January 2021

Role of chromosome translocations in human neoplasia

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7 January 2021

The histidine triad superfamily of nucleotide-binding proteins

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7 January 2021

The tumor suppressor protein Fhit. A novel interaction with tubulin

1 reference

7 January 2021

Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas

1 reference

7 January 2021

Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma

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7 January 2021

Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival

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7 January 2021

FHIT alterations in cancerous and non-cancerous cervical epithelium.

1 reference

7 January 2021

Clonal genetic alterations in the lungs of current and former smokers

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7 January 2021

Identifiers

DOI

10.1038/35106058

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28 November 2017

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