Diversity of the apoptotic response to chemotherapy in childhood leukemia (Q43882753)

27 November 2017

title

Diversity of the apoptotic response to chemotherapy in childhood leukemia (English)

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27 November 2017

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T Liu

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27 November 2017

E Raetz

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27 November 2017

P J Moos

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27 November 2017

S L Perkins

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27 November 2017

C S Bruggers

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27 November 2017

F Smith

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27 November 2017

W L Carroll

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27 November 2017

publication date

1 February 2002

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27 November 2017

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27 November 2017

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27 November 2017

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27 November 2017

page(s)

223-232

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

27 November 2017

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7 January 2021

Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983-1995.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Long-term results of treatment studies for childhood acute lymphoblastic leukemia: Pediatric Oncology Group studies from 1986-1994

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Survival after relapse in childhood acute lymphoblastic leukemia: impact of site and time to first relapse--the Children's Cancer Group Experience

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Relapsed lymphoblastic leukaemia in children: a continuing challenge

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Apoptosis and drug response

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

p53 in signaling checkpoint arrest or apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil, and prednisone for breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Altered expression of p53 and mdm-2 proteins at diagnosis is associated with early treatment failure in childhood acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

The proto-oncogene Bcl-2 and its role in regulating apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Bcl-xL modulates apoptosis induced by anticancer drugs and delays DEVDase and DNA fragmentation-promoting activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Bcl-2 family members in childhood acute lymphoblastic leukemia: relationships with features at presentation, in vitro and in vivo drug response and long-term clinical outcome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Caspases: enemies within

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Death receptors: signaling and modulation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Expression of apoptosis-controlling proteins in acute leukemia cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Induction of apoptosis in childhood acute leukemia by chemotherapeutic agents: failure to detect evidence of apoptosis in vivo

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Methods for the detection of apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Individualized methotrexate dosing in children with relapsed acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Clinical importance of speed of response to therapy in childhood lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Early response to therapy and outcome in childhood acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Induction of apoptosis in CD4+ prolymphocytic leukemia by deoxyadenosine and 2'-deoxycoformycin

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Phagocyte recognition of cells undergoing apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Comparative cytotoxicity of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Expression profile of MDM-2 proteins in chronic lymphocytic leukemia and their clinical relevance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Overexpression of MDM2 in acute childhood lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

The Bax alpha:Bcl-2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Bax:Bcl-2 ratio modulation by bryostatin 1 and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-B acute lymphoblastic leukemia cell line, Reh.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Elevated Bcl-2/Bax are a consistent feature of apoptosis resistance in B-cell chronic lymphocytic leukaemia and are correlated with in vivo chemoresistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

P53, MDM-2, BAX and BCL-2 and Drug Resistance in Chronic Lymphocytic Leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Antisense strategies for the treatment of hematological malignancies and solid tumors.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402360

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402360

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Dimensions Publication ID

27 November 2017

1050645569

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