Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors (Q43764227)

26 November 2017

title

Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors (English)

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26 November 2017

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Aoyama Y

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26 November 2017

Uenaka M

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26 November 2017

Kii M

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26 November 2017

Tanaka M

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26 November 2017

Konoike T

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26 November 2017

Hayasaki-Kajiwara Y

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26 November 2017

Naya N

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26 November 2017

Nakajima M

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26 November 2017

language of work or name

English

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publication date

1 November 2001

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Bioorganic & Medicinal Chemistry

26 November 2017

published in

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26 November 2017

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26 November 2017

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26 November 2017

page(s)

3065-3075

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Serine proteinases of mast cell and leukocyte granules. A league of their own.

26 November 2017

cites work

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7 January 2021

Recombinant expression of human mast cell proteases chymase and tryptase

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Increased chymase-dependent angiotensin II formation in human atherosclerotic aorta

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Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

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7 January 2021

Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide

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7 January 2021

Dog Mast Cell α-Chymase Activates Progelatinase B by Cleaving the Phe88-Gln89 and Phe91-Glu92 Bonds of the Catalytic Domain

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7 January 2021

Activation of angiotensin II-forming chymase in the cardiomyopathic hamster heart

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7 January 2021

Increased expression of mast cell chymase in the lungs of patients with congenital heart disease associated with early pulmonary vascular disease

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7 January 2021

Inhibition of chymase reduces vascular proliferation in dog grafted veins

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7 January 2021

Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors

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7 January 2021

Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold

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7 January 2021

Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors

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7 January 2021

Synthesis and structure-activity relationships of a new class of 1-oxacephem-based human chymase inhibitors

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7 January 2021

Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones

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7 January 2021

Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters

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7 January 2021

Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides

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7 January 2021

Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins

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7 January 2021

Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

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7 January 2021

Orally Active .beta.-Lactam Inhibitors of Human Leukocyte Elastase. 3. Stereospecific Synthesis and Structure-Activity Relationships for 3,3-Dialkylazetidin-2-ones

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7 January 2021

An Asymmetric Synthesis of L-694,458, a Human Leukocyte Elastase Inhibitor, via Novel Enzyme Resolution of beta-Lactam Esters

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7 January 2021

Synthesis of several new carbapenem antibiotics.

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7 January 2021

Diphenylphosphoryl azide. A new convenient reagent for a modified Curtus reaction and for the peptide synthesis

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7 January 2021

Catalysis by human leukocyte elastase: mechanistic insights into specificity requirements.

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7 January 2021

The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity

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7 January 2021

Characterization of chymase from human vascular tissues

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7 January 2021

10.1016/S0968-0896(01)00209-7

Identifiers

DOI

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26 November 2017

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