Glucosylceramide synthase inhibition enhances vincristine-induced cytotoxicity (Q43629518)

25 November 2017

title

Glucosylceramide synthase inhibition enhances vincristine-induced cytotoxicity (English)

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25 November 2017

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R S Olshefski

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25 November 2017

S Ladisch

series ordinal

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25 November 2017

language of work or name

English

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publication date

1 July 2001

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International Journal of Cancer

25 November 2017

published in

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25 November 2017

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25 November 2017

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25 November 2017

page(s)

131-138

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Functions of sphingolipids and sphingolipid breakdown products in cellular regulation

25 November 2017

cites work

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Ceramide formation during heat shock: a potential mediator of alpha B-crystallin transcription

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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Ceramide structure predicts tumor ganglioside immunosuppressive activity

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Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis.

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Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. Correlation with cyclin-dependent kinases

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Bcl-2 interrupts the ceramide-mediated pathway of cell death.

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Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

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Functions of ceramide in coordinating cellular responses to stress

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Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

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Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance

21 January 2018

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Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase

21 January 2018

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Improved Inhibitors of Glucosylceramide Synthase

21 January 2018

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Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

21 January 2018

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Programmed cell death induced by ceramide

21 January 2018

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Induction of programmed cell death and immunosuppression by exogenous sphingolipids are separate processes

21 January 2018

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Quantitative densitometric thin-layer chromatography of lipids using copper acetate reagent

21 January 2018

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Influence of cellular ganglioside depletion on tumor formation

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Two distinct modes of oncoprotein expression during apoptosis resistance in vincristine and daunorubicin multidrug-resistant HL60 cells.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.1301

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25 November 2017

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