Blockade of Tim-3 signaling restores the virus-specific CD8⁺ T-cell response in patients with chronic hepatitis B. (Q43426048)

23 November 2017

title

Blockade of Tim-3 signaling restores the virus-specific CD8⁺ T-cell response in patients with chronic hepatitis B. (English)

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23 November 2017

0 references

1 reference

Wei Wu

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23 November 2017

Yu Shi

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23 November 2017

Shuping Li

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23 November 2017

Yun Zhang

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23 November 2017

Yanning Liu

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23 November 2017

Yihua Wu

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23 November 2017

Zhi Chen

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23 November 2017

language of work or name

English

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publication date

1 May 2012

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European Journal of Immunology

23 November 2017

published in

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23 November 2017

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23 November 2017

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23 November 2017

page(s)

1180-1191

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Hepatitis B Virus Infection

23 November 2017

cites work

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https://api.crossref.org/works/10.1002%2FEJI.201141852

Chronic hepatitis B: update 2009

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Pathogenesis of hepatitis B virus infection

21 January 2018

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Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201141852

Longitudinal analysis of CD8+ T cells specific for structural and nonstructural hepatitis B virus proteins in patients with chronic hepatitis B: implications for immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201141852

The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses.

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201141852

PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

PD-1 and its ligands in tolerance and immunity

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.201141852

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Tim-3 expression on peripheral T cell subsets correlates with disease progression in hepatitis B infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Circulating Th17 cells frequency is associated with the disease progression in HBV infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Hepatitis B e-antigen persistency is associated with the properties of HBV-specific CD8 T cells in CHB patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141852

21 January 2018

Identifiers

DOI

10.1002/EJI.201141852

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23 November 2017

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