A disintegrin and metallopeptidase domain 3 (cyritestin) (Q43373906)

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mammalian protein found in Mus musculus

• a disintegrin and metalloprotease domain 3 (cyritestin)
• Adam3
• A disintegrin and metallopeptidase domain 3

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Language	Label	Description	Also known as
English	A disintegrin and metallopeptidase domain 3 (cyritestin)	mammalian protein found in Mus musculus	a disintegrin and metalloprotease domain 3 (cyritestin) Adam3 A disintegrin and metallopeptidase domain 3

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

F8VQ03

subclass of

protein

1 reference

stated in

UniProt

retrieved

25 October 2017

UniProt protein ID

F8VQ03

part of

disintegrin domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

Metallopeptidase, catalytic domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

Peptidase M12B, ADAM/reprolysin, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, extracellular domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Reprolysin domain, adamalysin-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

ADAM, cysteine-rich, protein family

1 reference

based on heuristic

inferred from protein domain or family

Disintegrin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase M12B, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

F8VQ03

encoded by

Adam3

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

F8VQ03

molecular function

metalloendopeptidase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IEA

protein binding

determination method or standard

IPI

4 references

retrieved

14 February 2019

stated in

Tex101 is essential for male fertility by affecting sperm migration into the oviduct in mice.

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IPI

retrieved

14 February 2019

stated in

Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IPI

retrieved

14 February 2019

stated in

GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IPI

retrieved

14 February 2019

stated in

Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IPI

metallopeptidase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IEA

cell component

plasma membrane

determination method or standard

IDA

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IEA

retrieved

14 February 2019

stated in

Synthesis, processing, and subcellular localization of mouse ADAM3 during spermatogenesis and epididymal sperm transport

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

cell surface

determination method or standard

IDA

4 references

retrieved

14 February 2019

stated in

Lack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal sperm

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

retrieved

14 February 2019

stated in

Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

retrieved

14 February 2019

stated in

GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

retrieved

14 February 2019

stated in

Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

membrane

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IEA

integral component of membrane

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IEA

membrane raft

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

sperm head

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Synthesis, processing, and subcellular localization of mouse ADAM3 during spermatogenesis and epididymal sperm transport

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

protein-containing complex

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

biological process

proteolysis

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IEA

single fertilization

determination method or standard

IGI

1 reference

retrieved

14 February 2019

stated in

Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IGI

binding of sperm to zona pellucida

determination method or standard

IDA

IMP

2 references

retrieved

14 February 2019

stated in

Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IMP

retrieved

14 February 2019

stated in

Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IDA

fertilization

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IMP

positive regulation of gene expression

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IMP

regulation of mRNA processing

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IMP

sperm motility

determination method or standard

IMP

1 reference

retrieved

27 March 2018

stated in

Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=F8VQ03&geneProductId=UniProtKB:F8VQ03

determination method or standard

IMP

flagellated sperm motility

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse

GOA

curator

UniProt

UniProt protein ID

F8VQ03

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:F8VQ03

determination method or standard

IMP

has part(s)

Peptidase M12B, ADAM/reprolysin

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

ADAM, cysteine-rich

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

Peptidase M12B, propeptide

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

EGF-like domain, extracellular

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

Reprolysin domain, adamalysin-type

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

EGF-like, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

Disintegrin domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

EGF-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/F8VQ03

Identifiers

RefSeq protein ID

NP_001311418

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

11497

NP_033749

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

11497

XP_011240415

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

11497

XP_011240416

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

11497

XP_017168013

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

11497

UniProt protein ID

F8VQ03

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

F8VQ03

Ensembl protein ID

ENSMUSP00000033958

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000033958

ENSMUSP00000126617

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126617

ENSMUSP00000132634

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132634

ENSMUSP00000127479

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000127479

ENSMUSP00000132620

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132620

ENSMUSP00000132651

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132651

ENSMUSP00000130818

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000130818

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q43373906&oldid=2023654312"