Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin (Q43258273)

17 November 2017

title

Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin (English)

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17 November 2017

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17 November 2017

Jenni E Keskitalo

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Marja K Pasanen

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17 November 2017

Pertti J Neuvonen

series ordinal

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17 November 2017

publication date

1 October 2009

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17 November 2017

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17 November 2017

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17 November 2017

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17 November 2017

page(s)

1617-1624

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Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin

17 November 2017

cites work

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Single nucleotide polymorphisms modify the transporter activity of ABCG2.

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Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.

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Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

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Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans

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Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe

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Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males

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ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.

21 January 2018

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Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/

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Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

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Lipid-lowering response to statins is affected by CYP3A5 polymorphism

21 January 2018

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Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS.

21 January 2018

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An improved and fully validated LC-MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma

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Pharmacogenetic study of statin therapy and cholesterol reduction

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Functional interaction of intestinal CYP3A4 and P-glycoprotein

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Disposition of oral and intravenous pravastatin in MRP2-deficient TR- rats

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ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin.

21 January 2018

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Polymorphisms in the multidrug resistance-1 (MDR1) gene influence the response to atorvastatin treatment in a gender-specific manner

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The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment

21 January 2018

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Statin-associated myopathy

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SLCO1B1 variants and statin-induced myopathy--a genomewide study

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SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin

21 January 2018

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Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population

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SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

21 January 2018

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Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics

21 January 2018

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Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/PGS.09.85

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17 November 2017

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