The perforin mediated apoptotic pathway in lung injury and fibrosis (Q43010408)

12 November 2017

The perforin mediated apoptotic pathway in lung injury and fibrosis (English)

1 reference

12 November 2017

1 reference

1 reference

H Miyazaki

1 reference

12 November 2017

K Kuwano

1 reference

12 November 2017

K Yoshida

1 reference

12 November 2017

T Maeyama

1 reference

12 November 2017

M Yoshimi

1 reference

12 November 2017

M Fujita

1 reference

12 November 2017

N Hagimoto

1 reference

12 November 2017

R Yoshida

1 reference

12 November 2017

Y Nakanishi

1 reference

12 November 2017

language of work or name

English

0 references

publication date

1 December 2004

1 reference

Journal of Clinical Pathology

12 November 2017

1 reference

12 November 2017

1 reference

12 November 2017

1 reference

12 November 2017

1292-1298

1 reference

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

12 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP).

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: implications for acute pulmonary inflammation

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Reduced Incidence and Delayed Onset of Diabetes in Perforin-deficient Nonobese Diabetic Mice

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Role of mesenchymal cell death in lung remodeling after injury.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Structure and function of human perforin

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Purified perforin induces target cell lysis but not DNA fragmentation

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1770527

P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis

16 August 2018

1 reference

12 December 2020

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

1 reference

12 December 2020

Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice

1 reference

12 December 2020

Induction of Apoptosis and Pulmonary Fibrosis in Mice in Response to Ligation of Fas Antigen

1 reference

12 December 2020

Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome

1 reference

12 December 2020

American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)

1 reference

12 December 2020

Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor

1 reference

12 December 2020

Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits

1 reference

12 December 2020

A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis

1 reference

12 December 2020

Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epithelium

1 reference

12 December 2020

Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung

1 reference

12 December 2020

Modes of epithelial cell death and repair in Sjögren's syndrome (SS).

1 reference

12 December 2020

The involvement of Fas-Fas ligand pathway in fibrosing lung diseases

1 reference

12 December 2020

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1 reference

12 December 2020

Identifiers

DOI

10.1136/JCP.2003.015495

1 reference

12 November 2017

1 reference

12 November 2017

PubMed publication ID

15563670

1 reference