Pregnenolone-16alpha-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms. (Q42816260)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15595924%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Pregnenolone-16alpha-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms (English)

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6 January 2020

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6 January 2020

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6 January 2020

Carylyn J Marek

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6 January 2020

Steven J Tucker

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6 January 2020

Dimitrios K Konstantinou

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6 January 2020

Lucy J Elrick

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6 January 2020

Dee Haefner

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6 January 2020

Graeme I Murray

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6 January 2020

Bryan Goodwin

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6 January 2020

language of work or name

English

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publication date

1 May 2005

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6 January 2020

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6 January 2020

volume

387

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6 January 2020

issue

Pt 3

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6 January 2020

page(s)

601-608

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Management of cirrhosis and ascites

6 January 2020

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1 reference

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27 May 2018

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27 May 2018

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

27 May 2018

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

27 May 2018

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27 May 2018

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Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

27 May 2018

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27 May 2018

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

27 May 2018

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Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential

27 May 2018

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P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

27 May 2018

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

27 May 2018

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An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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16 August 2018

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12 December 2020

Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

The role of inflammatory cells and cytochrome P450 in the potentiation of CCl4-induced liver injury by a single dose of retinol

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12 December 2020

Identifiers

DOI

10.1042/BJ20041598

1 reference

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6 January 2020

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6 January 2020

PubMed publication ID

15595924

1 reference

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