Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis. (Q42802652)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838072%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis (English)

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18 March 2020

Xiaolin Liang

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18 March 2020

Heying Pei

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18 March 2020

Liang Ma

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18 March 2020

Yan Ran

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18 March 2020

Jinying Chen

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18 March 2020

Guangcheng Wang

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18 March 2020

Lijuan Chen

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18 March 2020

language of work or name

English

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publication date

15 May 2014

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18 March 2020

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18 March 2020

volume

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18 March 2020

issue

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18 March 2020

page(s)

6163-6183

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Creative Commons Attribution 4.0 International

18 March 2020

start time

15 May 2014

1 reference

April 2022 Public Data File from Crossref

0 references

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056163

Global burden of obesity in 2005 and projections to 2030.

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The extent of the problem of obesity

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Medical hazards of obesity

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Epidemic trends of obesity with impact on metabolism and digestive diseases

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Alanine aminotransferase as a marker of non-alcoholic fatty liver disease in relation to type 2 diabetes mellitus and cardiovascular disease

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Nonalcoholic fatty liver disease

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Leptin signaling in the central nervous system and the periphery

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BMI-independent inverse relationship of plasma leptin levels with outcome in patients with acute pulmonary embolism

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Leptin impairs insulin signaling in rat adipocytes.

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Modulation of insulin activities by leptin

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Leptin impairs metabolic actions of insulin in isolated rat adipocytes.

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Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling

21 January 2018

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The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes

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Insulin sensitizers in nonalcoholic fatty liver disease and steatohepatitis: Current status

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Troglitazone: a review of its use in the management of type 2 diabetes mellitus

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Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11β-hydroxysteroid-dehydrogenase type 1

21 January 2018

1 reference

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Diet-induced obesity is associated with hyperleptinemia, hyperinsulinemia, hepatic steatosis, and glomerulopathy in C57Bl/6J mice

21 January 2018

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Transcriptional profiling reveals a role for RORalpha in regulating gene expression in obesity-associated inflammation and hepatic steatosis

21 January 2018

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High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase

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The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease

21 January 2018

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Protective roles of adiponectin in obesity-related fatty liver diseases: mechanisms and therapeutic implications.

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A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans

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Origins of ... tinctorial methods in histology

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Leptin signaling, adiposity, and energy balance

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12 December 2020

A link between leptin and steatosis in chronic hepatitis C? Time to weigh up the fats

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Molecular mediators of hepatic steatosis and liver injury

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12 December 2020

Metformin is effective in achieving biochemical response in patients with nonalcoholic fatty liver disease (NAFLD) not responding to lifestyle interventions.

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Fluorine in medicinal chemistry

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Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

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Nonalcoholic steatohepatitis: An expanded clinical entity

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12 December 2020

10.3390/MOLECULES19056163

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838072%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838072%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

24838072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838072%20AND%20SRC:MED&resulttype=core&format=json