Runx regulation of sphingolipid metabolism and survival signaling. (Q42722380)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587518%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Runx regulation of sphingolipid metabolism and survival signaling (English)

1 reference

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6 February 2020

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6 February 2020

Qifeng Zhang

1 reference

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6 February 2020

Anna Kilbey

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6 February 2020

Anne Terry

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6 February 2020

Alma Jenkins

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6 February 2020

Gillian Borland

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6 February 2020

Ewan R Cameron

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6 February 2020

James C Neil

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6 February 2020

language of work or name

English

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publication date

29 June 2010

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6 February 2020

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6 February 2020

volume

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6 February 2020

issue

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6 February 2020

page(s)

5860-5869

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Co-suppression of MDR1 (multidrug resistance 1) and GCS (glucosylceramide synthase) restores sensitivity to multidrug resistance breast cancer cells by RNA interference (RNAi).

6 February 2020

cites work

1 reference

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RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress

27 May 2018

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Lipid phosphate phosphatases and signaling

27 May 2018

1 reference

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Oncogene-induced senescence: an essential role for Runx

27 May 2018

1 reference

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Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival

27 May 2018

1 reference

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A role for ceramide in driving cancer cell resistance to doxorubicin.

27 May 2018

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TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species

27 May 2018

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Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts

27 May 2018

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Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2.

27 May 2018

1 reference

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Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment

27 May 2018

1 reference

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Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer

27 May 2018

1 reference

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Mitochondrial ceramide and the induction of apoptosis

27 May 2018

1 reference

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The RUNX genes: gain or loss of function in cancer

27 May 2018

1 reference

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Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system.

27 May 2018

1 reference

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RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53.

27 May 2018

1 reference

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Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer

27 May 2018

1 reference

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27 May 2018

1 reference

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Sphingosine-1-phosphate: an enigmatic signalling lipid

27 May 2018

1 reference

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Upstream and downstream targets of RUNX proteins.

27 May 2018

1 reference

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Sphingosine kinase, sphingosine-1-phosphate, and apoptosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

Glucosylceramide synthase and apoptosis

27 May 2018

1 reference

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Sphingosine in apoptosis signaling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

Ganglioside G(M3) overexpression induces apoptosis and reduces malignant potential in murine bladder cancer

27 May 2018

1 reference

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The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons

27 May 2018

1 reference

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RUNX: a trilogy of cancer genes.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 gene

27 May 2018

1 reference

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Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors

27 May 2018

1 reference

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Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

27 May 2018

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Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation

27 May 2018

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Overexpression of AML1 renders a T hybridoma resistant to T cell receptor-mediated apoptosis

27 May 2018

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Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

27 May 2018

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Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

27 May 2018

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The v-Jun oncoprotein replaces p39 c-Jun as the predominant AP-1 constituent in ASV17-transformed fibroblasts: implications for SAPK/JNK-mediated signal transduction.

27 May 2018

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

27 May 2018

1 reference

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Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

27 May 2018

1 reference

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Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

16 August 2018

1 reference

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UVB irradiation reduces the half-life and transactivation potential of the human papillomavirus 16 E2 protein

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

Sialylation and sulfation of lactosylceramide distinctly regulate anchorage-independent growth, apoptosis, and gene expression in 3LL Lewis lung carcinoma cells

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

Proviral insertion indicates a dominant oncogenic role for Runx1/AML-1 in T-cell lymphoma.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906707

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

16 August 2018

1 reference

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Exchange of C(16)-ceramide between phospholipid vesicles

16 August 2018

1 reference

12 December 2020

Runx2: a novel oncogenic effector revealed by in vivo complementation and retroviral tagging

1 reference

12 December 2020

Programmed cell death induced by ceramide

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12 December 2020

Ceramide and apoptosis

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12 December 2020

Runx2 and MYC collaborate in lymphoma development by suppressing apoptotic and growth arrest pathways in vivo

1 reference

12 December 2020

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells

1 reference

12 December 2020

A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc

1 reference

12 December 2020

10.1158/0008-5472.CAN-10-0726

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587518%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587518%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

20587518

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20587518%20AND%20SRC:MED&resulttype=core&format=json