Synthesis and pharmacological evaluation of fluorine-containing D₃ dopamine receptor ligands. (Q42705882)

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23 January 2020

title

Synthesis and pharmacological evaluation of fluorine-containing D₃ dopamine receptor ligands (English)

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23 January 2020

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23 January 2020

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23 January 2020

Robert H Mach

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23 January 2020

Shihong Li

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23 January 2020

Jinbin Xu

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23 January 2020

Michelle Taylor

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23 January 2020

David Ho

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23 January 2020

Robert R Luedtke

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23 January 2020

language of work or name

English

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publication date

24 February 2011

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Journal of Medicinal Chemistry

23 January 2020

published in

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volume

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issue

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23 January 2020

page(s)

1555-1564

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Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models

23 January 2020

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[(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin- 1-yl)butyl]benzamide, a selective radioligand for dopamine D(3) receptors. I. In vitro characterization

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Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors

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Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor

27 May 2018

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Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

27 May 2018

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BP 897, a selective dopamine D3 receptor ligand with therapeutic potential for the treatment of cocaine-addiction.

27 May 2018

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Progress in developing D3 dopamine receptor ligands as potential therapeutic agents for neurological and neuropsychiatric disorders

27 May 2018

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Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists

27 May 2018

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Effects of the D(3) dopamine receptor antagonist, U99194A, on brain stimulation and d-amphetamine reward, motor activity, and c-fos expression in ad libitum fed and food-restricted rats

27 May 2018

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Characterization of (125)I-IABN, a novel azabicyclononane benzamide selective for D2-like dopamine receptors

27 May 2018

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Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A

27 May 2018

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Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

27 May 2018

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Induction of dopamine D3 receptor expression as a mechanism of behavioral sensitization to levodopa

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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The selective D(3) receptor antagonist, S33084, improves parkinsonian-like motor dysfunction but does not affect L-DOPA-induced dyskinesia in 6-hydroxydopamine hemi-lesioned rats

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Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease.

16 August 2018

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Synthesis of new carbon-11-labeled carboxamide derivatives as potential PET dopamine D3 receptor radioligands

16 August 2018

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Dopamine D3 receptor agonist delivery to a model of Parkinson's disease restores the nigrostriatal pathway and improves locomotor behavior.

16 August 2018

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Central dopamine receptors: general considerations (Part 1)

16 August 2018

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The dopamine D3 receptor and drug addiction

16 August 2018

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N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands

16 August 2018

1 reference

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Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21348515

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM101323B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21348515%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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23 January 2020

PubMed publication ID

21348515

1 reference

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