Evidence for a centrally located gate in the pore of a serotonin-gated ion channel. (Q42671582)

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scientific article published on March 2002

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English	Evidence for a centrally located gate in the pore of a serotonin-gated ion channel.	scientific article published on March 2002

Statements

instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

11880493

retrieved

4 November 2017

title

Evidence for a centrally located gate in the pore of a serotonin-gated ion channel (English)

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stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

main subject

serotonin

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author

Sandip Panicker

series ordinal

1

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Europe PubMed Central

PMC publication ID

6758895

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

author name string

Hans Cruz

series ordinal

2

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Europe PubMed Central

PMC publication ID

6758895

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

Christine Arrabit

series ordinal

3

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Europe PubMed Central

PMC publication ID

6758895

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

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12 May 2020

Paul A Slesinger

series ordinal

4

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Europe PubMed Central

PMC publication ID

6758895

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

language of work or name

English

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publication date

1 March 2002

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stated in

Europe PubMed Central

PubMed publication ID

11880493

retrieved

4 November 2017

published in

Journal of Neuroscience

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

volume

22

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stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

issue

5

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stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

page(s)

1629-1639

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Europe PubMed Central

PMC publication ID

6758895

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

cites work

Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gated access to the pore of a voltage-dependent K+ channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the use of thiol-modifying agents to determine channel topology

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory influence via 5-HT3 receptors on the induction of LTP in mossy fiber-CA3 system of guinea-pig hippocampal slices

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strychnine activates neuronal alpha7 nicotinic receptors after mutations in the leucine ring and transmitter binding site domains

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PubMed

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12 December 2020

based on heuristic

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Induction and maintenance of ganglionic long-term potentiation require activation of 5-hydroxytryptamine (5-HT3) receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11880493

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12 December 2020

based on heuristic

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Modulation of afferent-evoked neurotransmission by 5-HT3 receptors in young rat dorsal horn neurones in vitro: a putative mechanism of 5-HT3 induced anti-nociception

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic ionotropic receptors and the control of transmitter release.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-induced closure of constitutively open gamma-aminobutyric acid channels with mutated M2 domains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The location of the gate in the acetylcholine receptor channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of 5-HT3 receptor-mediated ion current by divalent metal cations in NCB-20 neuroblastoma cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic receptors at the amino acid level

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histidine scanning mutagenesis of basic residues of the S4 segment of the shaker k+ channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Threonine-for-leucine mutation within domain M2 of the neuronal alpha(7) nicotinic receptor converts 5-hydroxytryptamine from antagonist to agonist.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substitutions of the Highly Conserved M2 Leucine Create Spontaneously Opening ρ1 γ-Aminobutyric Acid Receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ligand Gated Ion Channel Database

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paradoxical allosteric effects of competitive inhibitors on neuronal α7 nicotinic receptor mutants

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine receptor channel imaged in the open state

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nervous system distribution of the serotonin 5-HT3 receptor mRNA.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT3 antiemetic therapy for patients with breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutating the highly conserved second membrane-spanning region 9' leucine residue in the alpha(1) or beta(1) subunit produces subunit-specific changes in the function of human alpha(1)beta(1) gamma-aminobutyric Acid(A) receptors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A distinct contribution of the delta subunit to acetylcholine receptor channel activation revealed by mutations of the M2 segment

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 5-HT3B subunit is a major determinant of serotonin-receptor function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11880493

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.22-05-01629.2002

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

PMC publication ID

6758895

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

PubMed publication ID

11880493

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758895

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6758895&resulttype=core&format=json

retrieved

12 May 2020

 

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