Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing (Q42605401)

3 November 2017

title

Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing (English)

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3 November 2017

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3 November 2017

Michael Antoniou

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3 November 2017

Tracey Mustoe

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3 November 2017

Steven Williams

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3 November 2017

Jolyon Holdstock

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3 November 2017

Ernesto Yague

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3 November 2017

Tony Mulcahy

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3 November 2017

Mark Griffiths

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3 November 2017

Sian Edwards

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3 November 2017

Panayiotis A Ioannou

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3 November 2017

Andrew Mountain

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3 November 2017

Robert Crombie

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3 November 2017

publication date

1 September 2003

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3 November 2017

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3 November 2017

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3 November 2017

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3 November 2017

page(s)

269-279

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Do LCRs open chromatin domains?

3 November 2017

cites work

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7 January 2021

Insulators: many functions, many mechanisms.

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7 January 2021

Locus control regions, chromatin activation and transcription

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7 January 2021

Locus control regions: coming of age at a decade plus

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7 January 2021

The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

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7 January 2021

A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

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7 January 2021

Locus control region function and heterochromatin-induced position effect variegation

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7 January 2021

Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription.

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7 January 2021

Transcriptional enhancers act in cis to suppress position-effect variegation

1 reference

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7 January 2021

Expression of a retrovirally transduced gene under control of an internal housekeeping gene promoter does not persist due to methylation and is restored partially by 5-azacytidine treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals

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7 January 2021

Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Looping versus linking: toward a model for long-distance gene activation

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Activation by locus control regions?

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Far upstream regions of class II MHC Ea are necessary for position-independent, copy-dependent expression of Ea transgene

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

The human growth hormone gene is regulated by a multicomponent locus control region

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Muscle-specific locus control region activity associated with the human desmin gene

1 reference

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7 January 2021

Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

A locus control region in the T cell receptor alpha/delta locus

1 reference

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7 January 2021

Analysis of mice with single and multiple copies of transgenes reveals a novel arrangement for the lambda5-VpreB1 locus control region

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues

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https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

CpG islands and genes

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https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Alternative chromatin structure at CpG islands

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https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Transcriptional regulation of the human TATA binding protein gene

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

The gene for the TATA binding protein (TBP) that contains a highly polymorphic protein coding CAG repeat maps to 6q27.

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Physical mapping at 6q27 of the locus for the TATA box-binding protein, the DNA-binding subunit of TFIID and a component of SL1 and TFIIIB, strongly suggests that it is single copy in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Linkage of TATA-binding protein and proteasome subunit C5 genes in mice and humans reveals synteny conserved between mammals and invertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Recent human-specific spreading of a subtelomeric domain

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Identification of mRNAs associated with programmed cell death in immature thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Cloning of mouse RP-8 cDNA and its expression during apoptosis of lymphoid and myeloid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Genomic structure of the human TATA-box-binding protein (TBP)

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Two homologous genes, originated by duplication, encode the human hnRNP proteins A2 and A1

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Structure and expression of the gene (HNRPA2B1) encoding the human hnRNP protein A2/B1

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Disruption of downstream chromatin directed by a transcriptional activator

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https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

A human RNA polymerase II complex containing factors that modify chromatin structure

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https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Chromatin modification by DNA tracking

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

RNA polymerase II elongation through chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Intergenic transcription and transinduction of the human β-globin locus

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Intergenic transcription occurs throughout the human IL-4/IL-13 gene cluster

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Intergenic transcription in the human beta-globin gene cluster

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

The human Surfeit locus

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0888-7543%2803%2900107-1

7 January 2021

10.1016/S0888-7543(03)00107-1

Identifiers

DOI

1 reference

release_kmgdobihjvgp3iwyvtbugjr7ja

3 November 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/kmgdobihjvgp3iwyvtbugjr7ja

24 November 2022

mapped directly with Wikidata item

1 reference