Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation (Q42502038)

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English	Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation	scientific article

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Europe PubMed Central

PubMed publication ID

1 November 2017

Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation (English)

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1 November 2017

apoptotic process

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author name string

Yang Y

1

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1 November 2017

Cheng JZ

2

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1 November 2017

Singhal SS

3

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1 November 2017

Saini M

4

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1 November 2017

Pandya U

5

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1 November 2017

Awasthi S

6

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1 November 2017

Awasthi YC

7

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1 November 2017

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publication date

7 March 2001

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1 November 2017

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11

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Journal of Biological Chemistry

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1 November 2017

276

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1 November 2017

22

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1 November 2017

19220-19230

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1 November 2017

Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway

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Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

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Myeloperoxidase is involved in H2O2-induced apoptosis of HL-60 human leukemia cells

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Induction of apoptosis of monocyte-macrophage lineage cells by 5-S-GAD.

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Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation.

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Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells.

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Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.

1 reference

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Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells.

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Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes

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Purification and characterization of human plasma glutathione peroxidase: a selenoglycoprotein distinct from the known cellular enzyme

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The selenoenzyme phospholipid hydroperoxide glutathione peroxidase

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

1 reference

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21 January 2018

Human glutathione S-transferases

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Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue

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Zeta, a novel class of glutathione transferases in a range of species from plants to humans

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Glutathione peroxidase activity of glutathione-s-transferases purified from rat liver

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Interrelationship between anionic and cationic forms of glutathione S-transferases of human liver

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Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties

1 reference

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Subunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antisera

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The role of human glutathione S-transferases hGSTA1-1 and hGSTA2-2 in protection against oxidative stress

1 reference

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21 January 2018

Cloning and heterologous expression of cDNA encoding class Alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl compounds

1 reference

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21 January 2018

Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation

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21 January 2018

Identification of a novel human glutathione S-transferase using bioinformatics

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21 January 2018

Lipid photooxidation in erythrocyte ghosts: sensitization of the membranes toward ascorbate- and superoxide-induced peroxidation and lysis

1 reference

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21 January 2018

Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Reversal of typical multidrug resistance by cyclosporin and its non-immunosuppressive analogue SDZ PSC 833 in Chinese hamster ovary cells expressing the mdr1 phenotype

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Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis

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Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production

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Signal transduction by tumor necrosis factor mediated by JNK protein kinases

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

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Inhibition of microsomal lipid peroxidation by glutathione and glutathione transferases B and AA. Role of endogenous phospholipase A2.

1 reference

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Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells.

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Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis

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Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity

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Sequential protein kinase reactions controlling cell growth and differentiation

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Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

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Nomenclature for human glutathione transferases

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Characterization of the hydroperoxide-reducing activity of human plasma

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21 January 2018

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10.1074/JBC.M100551200

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Europe PubMed Central

PubMed publication ID

1 November 2017

release_24k2q4bx5jex3kgae6so5fvhvy

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24 November 2022

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1 November 2017

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