p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity (Q42437308)

31 October 2017

title

p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity (English)

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31 October 2017

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31 October 2017

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31 October 2017

Isabella Castellano

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Paola Bernabei

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Emilia Turco

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31 October 2017

Paola Defilippi

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31 October 2017

Giusy Tornillo

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31 October 2017

Angela Rita Elia

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31 October 2017

Michela Spadaro

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31 October 2017

Brigitte Bisaro

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31 October 2017

Maria Del Pilar Camacho-Leal

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31 October 2017

Alessandra Pincini

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31 October 2017

Paolo Provero

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31 October 2017

publication date

1 July 2013

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31 October 2017

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31 October 2017

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31 October 2017

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31 October 2017

page(s)

1422-1433

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The mammary myoepithelial cell

31 October 2017

cites work

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Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland

21 January 2018

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Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

21 January 2018

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Deciphering the mammary epithelial cell hierarchy

21 January 2018

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Delineating the epithelial hierarchy in the mouse mammary gland.

21 January 2018

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CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells

21 January 2018

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Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

21 January 2018

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Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland

21 January 2018

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Detection and analysis of mammary gland stem cells

21 January 2018

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Cells of origin in cancer

21 January 2018

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Triple negative breast cancer: unmet medical needs

21 January 2018

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

21 January 2018

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BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells

21 January 2018

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Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate

21 January 2018

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Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.

21 January 2018

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c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.

21 January 2018

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CAS proteins in normal and pathological cell growth control

21 January 2018

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p130Cas: a versatile scaffold in signaling networks

21 January 2018

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Integrin signalling adaptors: not only figurants in the cancer story

21 January 2018

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p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

21 January 2018

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p130Cas is an essential transducer element in ErbB2 transformation

21 January 2018

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p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1

21 January 2018

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Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

21 January 2018

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A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland

21 January 2018

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Stem cell factor receptor/c-Kit: from basic science to clinical implications

21 January 2018

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Lentiviral transduction of mammary stem cells for analysis of gene function during development and cancer

21 January 2018

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Routine assessment of prognostic factors in breast cancer using a multicore tissue microarray procedure

21 January 2018

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Differentiation of separated mouse mammary luminal epithelial and myoepithelial cells cultured on EHS matrix analyzed by indirect immunofluorescence of cytoskeletal antigens

21 January 2018

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Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland

21 January 2018

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Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

21 January 2018

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Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors

21 January 2018

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Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.

21 January 2018

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Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

21 January 2018

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The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium

21 January 2018

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GATA-3 and the regulation of the mammary luminal cell fate

21 January 2018

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Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling

21 January 2018

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FoxM1 regulates mammary luminal cell fate

21 January 2018

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An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate

21 January 2018

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Slug and Sox9 cooperatively determine the mammary stem cell state

21 January 2018

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NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation

21 January 2018

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p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells

21 January 2018

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Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

21 January 2018

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Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

21 January 2018

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Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies

21 January 2018

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Hallmarks of 'BRCAness' in sporadic cancers

21 January 2018

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Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

21 January 2018

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KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1403

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31 October 2017

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