Increased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3'-monoxime (Q42426426)

31 October 2017

Increased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3'-monoxime (English)

1 reference

31 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27185663%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

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6 June 2020

Daniel Schachner

1 reference

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6 June 2020

Christoph S Grojer

1 reference

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6 June 2020

Maddalena Donati

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6 June 2020

publication date

14 May 2016

1 reference

31 October 2017

Vascular Pharmacology

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6 June 2020

volume

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6 June 2020

page(s)

47-56

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Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases

6 June 2020

cites work

1 reference

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Metabolic reprogramming: the emerging concept and associated therapeutic strategies

28 May 2018

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STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation

28 May 2018

1 reference

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MicroRNA-143 acts as a tumor suppressor by targeting hexokinase 2 in human prostate cancer.

28 May 2018

1 reference

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Glucose, glycolysis and lymphocyte responses

28 May 2018

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The Ins and Outs of Small GTPase Rac1 in the Vasculature.

28 May 2018

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Quinolone-indolone conjugate induces apoptosis by inhibiting the EGFR-STAT3-HK2 pathway in human cancer cells

28 May 2018

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Activated AMPK boosts the Nrf2/HO-1 signaling axis--A role for the unfolded protein response

28 May 2018

1 reference

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Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages

28 May 2018

1 reference

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Glycolytic switch in response to betulinic acid in non-cancer cells

28 May 2018

1 reference

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Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy

28 May 2018

1 reference

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The Warburg effect: evolving interpretations of an established concept

28 May 2018

1 reference

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Astragaloside IV inhibits platelet-derived growth factor-BB-stimulated proliferation and migration of vascular smooth muscle cells via the inhibition of p38 MAPK signaling

28 May 2018

1 reference

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STAT3 Activities and Energy Metabolism: Dangerous Liaisons.

28 May 2018

1 reference

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Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR-STAT3/microRNA143 pathway

28 May 2018

1 reference

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Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway

28 May 2018

1 reference

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Indirubin-3'-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration

28 May 2018

1 reference

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Nrf2 affects the efficiency of mitochondrial fatty acid oxidation.

28 May 2018

1 reference

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12/15-lipoxygenase contributes to platelet-derived growth factor-induced activation of signal transducer and activator of transcription 3

28 May 2018

1 reference

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Metabolic reprogramming as a novel regulator of skeletal muscle development and regeneration

28 May 2018

1 reference

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Influence of glucose metabolism on vascular smooth muscle cell proliferation.

28 May 2018

1 reference

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Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

miR-143 regulates hexokinase 2 expression in cancer cells

28 May 2018

1 reference

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Resveratrol inhibits migration and Rac1 activation in EGF- but not PDGF-activated vascular smooth muscle cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Vascular smooth muscle cell motility: From migration to invasion

28 May 2018

1 reference

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Metabolism strikes back: metabolic flux regulates cell signaling

28 May 2018

1 reference

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Regulation and cytoprotective role of hexokinase III

28 May 2018

1 reference

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Marine Natural Products as Inhibitors of Hypoxic Signaling in Tumors

28 May 2018

1 reference

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HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism

28 May 2018

1 reference

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Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor

28 May 2018

1 reference

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Big roles for small GTPases in the control of directed cell movement

28 May 2018

1 reference

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On respiratory impairment in cancer cells

28 May 2018

1 reference

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Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver

28 May 2018

1 reference

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The species concept and its application to tailed phages

28 May 2018

1 reference

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Induction of PDGF-responsive genes in vascular smooth muscle. Implications for the early response to vessel injury

28 May 2018

1 reference

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Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Indirubin-3'-oxime induces mitochondrial dysfunction and triggers growth inhibition and cell cycle arrest in human neuroblastoma cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Metabolic control analysis of the Warburg-effect in proliferating vascular smooth muscle cells

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Sphingosine-1-phosphate stimulates smooth muscle cell migration through galpha(i)- and pi3-kinase-dependent p38(MAPK) activation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Competitive Inhibition of Rat Brain Hexokinase by 2‐Deoxyglucose, Glucosamine, and Metrizamide

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4939873

Enhancement of doxorubicin content by the antitumor drug lonidamine in resistant ehrlich ascites tumor cells through modulation of energy metabolism

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.002

10.1016/J.VPH.2016.05.002

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27185663%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27185663%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

27185663

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27185663%20AND%20SRC:MED&resulttype=core&format=json