Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice (Q42290204)

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scientific article published on 27 March 2017

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English	Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice	scientific article published on 27 March 2017

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instance of

scholarly article

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Europe PubMed Central

PMC publication ID

5409082

retrieved

19 October 2017

title

Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice (English)

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

main subject

Alzheimer's disease

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author name string

Gabrielle L Sell

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1

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

Thomas B Schaffer

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2

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

Seth S Margolis

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3

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Europe PubMed Central

PMC publication ID

5409082

retrieved

19 October 2017

language of work or name

English

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publication date

27 March 2017

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

published in

Journal of Clinical Investigation

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

volume

127

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

issue

5

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

page(s)

1646-1650

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Europe PubMed Central

PMC publication ID

5409082

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19 October 2017

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Selective alterations of neurons and circuits related to early memory loss in Alzheimer's disease.

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Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.

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26 October 2017

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

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26 October 2017

EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation

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Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein

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EphB receptors couple dendritic filopodia motility to synapse formation

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Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

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Synaptic slaughter in Alzheimer's disease

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Clinical practice. Early Alzheimer's disease

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26 October 2017

Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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26 October 2017

Burst spiking of a single cortical neuron modifies global brain state

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29 May 2018

Ethological study of the behaviour of the albino rat in a passive-avoidance test

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29 May 2018

When Is the Hippocampus Involved in Recognition Memory?

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17 August 2018

Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

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17 August 2018

Dendrite and dendritic spine alterations in Alzheimer models

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17 August 2018

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

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17 August 2018

Identifiers

DOI

10.1172/JCI85504

1 reference

stated in

Europe PubMed Central

PMC publication ID

5409082

retrieved

19 October 2017

PMC publication ID

5409082

1 reference

stated in

Europe PubMed Central

PMC publication ID

5409082

retrieved

19 October 2017

PubMed publication ID

28346227

1 reference

stated in

Europe PubMed Central

PMC publication ID

5409082

retrieved

19 October 2017

 

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