A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis (Q42174912)

18 October 2017

A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis (English)

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18 October 2017

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18 October 2017

Yannick Arlot-Bonnemains

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Yannick Arlot-Bonnemains

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18 October 2017

Ignacio Pérez de Castro

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Ignacio Pérez de Castro

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Diego Megías

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Cristina Aguirre-Portolés

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18 October 2017

Benedicte Martin

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18 October 2017

Gonzalo Fernández-Miranda

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18 October 2017

Andrea Klotzbucher

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18 October 2017

Michael H G Kubbutat

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18 October 2017

14 December 2011

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18 October 2017

Frontiers in Oncology

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18 October 2017

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18 October 2017

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describes a project that uses

18 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3355891/fullTextXML

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cites work

Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis

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26 October 2017

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SUMOylation modulates the function of Aurora-B kinase

26 October 2017

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26 October 2017

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RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin

26 October 2017

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Dissecting the role of Aurora A during spindle assembly

26 October 2017

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Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

26 October 2017

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26 October 2017

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26 October 2017

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SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis

26 October 2017

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26 October 2017

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SUMO-mediated regulation of synaptonemal complex formation during meiosis

26 October 2017

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26 October 2017

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STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis

26 October 2017

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Mitotic mechanics: the auroras come into view

26 October 2017

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26 October 2017

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AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer

26 October 2017

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SUMO-2/3 regulates topoisomerase II in mitosis

26 October 2017

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26 October 2017

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26 October 2017

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26 October 2017

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The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

26 October 2017

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AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

26 October 2017

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Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

26 October 2017

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26 October 2017

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26 October 2017

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Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas.

26 October 2017

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

26 October 2017

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Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

26 October 2017

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Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

26 October 2017

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Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

26 October 2017

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SUMO--nonclassical ubiquitin

26 October 2017

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

26 October 2017

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

26 October 2017

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The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

26 October 2017

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A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

26 October 2017

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Regulation of the yeast HO gene

26 October 2017

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

26 October 2017

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Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis.

26 October 2017

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SUMO-dependent regulation of centrin-2.

29 May 2018

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Regulation of mitotic spindle asymmetry by SUMO and the spindle-assembly checkpoint in yeast

17 August 2018

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Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.

17 August 2018

1 reference

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Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

17 August 2018

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Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas.

17 August 2018

1 reference

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Dynamic association of a tumor amplified kinase, Aurora‐A, with the centrosome and mitotic spindle

17 August 2018

1 reference

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Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer.

17 August 2018

1 reference

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Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers

17 August 2018

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Degradation of human Aurora-A protein kinase is mediated by hCdh1

17 August 2018

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12 December 2020

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

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12 December 2020

Detection of protein SUMOylation in vivo

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12 December 2020

Amplification/overexpression of a mitotic kinase gene in human bladder cancer

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12 December 2020

A role for Ubc9 in tumorigenesis

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12 December 2020

A novel mechanism for activation of the protein kinase Aurora A

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12 December 2020

Identification of a functional destruction box in the Xenopus laevis aurora-A kinase pEg2

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12 December 2020

Identifiers

DOI

10.3389/FONC.2011.00050

1 reference

release_xkblfxne5zgntbvrqg27owm4e4

18 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xkblfxne5zgntbvrqg27owm4e4

24 November 2022

mapped directly with Wikidata item

1 reference

18 October 2017

PubMed publication ID

22649767

1 reference