Genetic analysis of Down syndrome facilitated by mouse chromosome engineering. (Q42102299)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22126738%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Genetic analysis of Down syndrome facilitated by mouse chromosome engineering (English)

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17 January 2020

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Alexander M Kleschevnikov

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17 January 2020

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17 January 2020

Li Zhang

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17 January 2020

Dawei Fu

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17 January 2020

Pavel V Belichenko

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17 January 2020

Chunhong Liu

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17 January 2020

Annie Pao

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17 January 2020

Steven J Clapcote

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17 January 2020

William C Mobley

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17 January 2020

Y Eugene Yu

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17 January 2020

publication date

1 January 2012

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17 January 2020

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17 January 2020

volume

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17 January 2020

issue

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17 January 2020

page(s)

8-12

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Genetic analysis of Down syndrome-associated heart defects in mice.

17 January 2020

cites work

1 reference

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Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.

29 May 2018

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GABAB-GIRK2-mediated signaling in Down syndrome.

29 May 2018

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Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

29 May 2018

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Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse

29 May 2018

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A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

29 May 2018

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Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome

29 May 2018

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A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

29 May 2018

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The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

29 May 2018

1 reference

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The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome

29 May 2018

1 reference

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Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

29 May 2018

1 reference

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Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

29 May 2018

1 reference

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An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

29 May 2018

1 reference

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A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

29 May 2018

1 reference

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A new mouse model for Down syndrome

29 May 2018

1 reference

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Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome.

29 May 2018

1 reference

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Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

29 May 2018

1 reference

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Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

29 May 2018

1 reference

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Cognitive functions of the basal forebrain

29 May 2018

1 reference

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Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

29 May 2018

1 reference

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Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

29 May 2018

1 reference

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Down syndrome phenotypes: the consequences of chromosomal imbalance

29 May 2018

1 reference

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

29 May 2018

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Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

29 May 2018

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The neuropathology of Alzheimer's disease: a review with pathogenetic, aetiological and therapeutic considerations

29 May 2018

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Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

29 May 2018

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The consequences of chromosome imbalance

29 May 2018

1 reference

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Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome

29 May 2018

1 reference

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Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities

17 August 2018

1 reference

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Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence

17 August 2018

1 reference

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Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model

17 August 2018

1 reference

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Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

17 August 2018

1 reference

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DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects

17 August 2018

1 reference

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Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome

17 August 2018

1 reference

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Anomalies in Down syndrome individuals in a large population-based registry

17 August 2018

1 reference

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Mapping of the Down syndrome phenotype on chromosome 21 at the molecular level.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3329253

Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome

17 August 2018

1 reference

12 December 2020

Biology and outcome of childhood acute megakaryoblastic leukemia: a single institution's experience

1 reference

12 December 2020

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

1 reference

12 December 2020

Hematopoietic defects in the Ts1Cje mouse model of Down syndrome

1 reference

12 December 2020

Identifiers

DOI

10.4161/BBUG.3.1.17696

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22126738%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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17 January 2020

PubMed publication ID

22126738

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