Disruption of integrin-fibronectin complexes by allosteric but not ligand-mimetic inhibitors. (Q42001098)

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21 February 2020

title

Disruption of integrin-fibronectin complexes by allosteric but not ligand-mimetic inhibitors (English)

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21 February 2020

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21 February 2020

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21 February 2020

Susan E Craig

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21 February 2020

Sarah K Byron

series ordinal

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21 February 2020

Thomas A Jowitt

series ordinal

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21 February 2020

language of work or name

English

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publication date

1 December 2014

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21 February 2020

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21 February 2020

volume

464

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issue

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page(s)

301-313

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Integrins: bidirectional, allosteric signaling machines

21 February 2020

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Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

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Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

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Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster

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The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

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Conformational inactivation induces immunogenicity of the receptor-binding pocket of a bacterial adhesin

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21 January 2018

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The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

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Identifiers

DOI

10.1042/BJ20141047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25333419%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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