Evaluation of the alpha 2-adrenoceptor blocking properties of buspirone and ipsapirone in healthy subjects. Relationship with the plasma concentration of the common metabolite 1-(2-pyrimidinyl)-piperazine (Q41872669)

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scientific article published on March 1995

Language	Label	Description	Also known as
English	Evaluation of the alpha 2-adrenoceptor blocking properties of buspirone and ipsapirone in healthy subjects. Relationship with the plasma concentration of the common metabolite 1-(2-pyrimidinyl)-piperazine	scientific article published on March 1995

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Evaluation of the alpha 2-adrenoceptor blocking properties of buspirone and ipsapirone in healthy subjects. Relationship with the plasma concentration of the common metabolite 1-(2-pyrimidinyl)-piperazine (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

I Berlin

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

S Chalon

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

C Payan

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

G Schöllnhammer

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

F Cesselin

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

O Varoquaux

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

A J Puech

7

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

0 references

publication date

1 March 1995

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

39

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

243-249

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Chronic treatment with an anxiolytic dose of the 5-HT1A agonist ipsapirone does not alter ipsapirone acute neuroendocrine effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder

1 reference

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5 June 2018

Assessment of α2 adrenergic autoreceptor function in humans: Effects of oral yohimbine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Metabolism and disposition of buspirone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Abnormal regulation of noradrenergic function in panic disorders. Effects of clonidine in healthy subjects and patients with agoraphobia and panic disorder

1 reference

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5 June 2018

Different effects of intracerebral and systemic administration of buspirone in the forced swimming test: involvement of a metabolite

1 reference

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5 June 2018

Blockade of alpha 2-adrenoceptors by 1-(2-pyrimidinyl)-piperazine (PmP) in vivo and its relation to the activity of buspirone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Reversal of helpless behavior in rats by putative 5-HT1A agonists.

1 reference

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5 June 2018

Buspirone. A preliminary review of its pharmacological properties and therapeutic efficacy as an anxiolytic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

1-(2-Pyrimidinyl)-piperazine as active metabolite of buspirone in man and rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

3H-TVX Q 7821: identification of 5-HT1 binding sites as target for a novel putative anxiolytic

1 reference

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5 June 2018

Assessment of MK-912, an alpha 2-adrenoceptor antagonist, with use of intravenous clonidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Panic and hypertension associated with single dose of buspirone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test

1 reference

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5 June 2018

Topics in clinical pharmacology: buspirone: a new nonbenzodiazepine anxiolytic agent

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1995.TB04443.X

21 January 2018

Buspirone in clinical practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Cerebral pharmacokinetics of ipsapirone in rats after different routes of administration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Efficacy and safety of a putative anxiolytic agent: ipsapirone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

Neuroendocrine effects of azapirones.

1 reference

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5 June 2018

Corticotropin and cortisol secretion after central 5-hydroxytryptamine-1A (5-HT1A) receptor activation: effects of 5-HT receptor and beta-adrenoceptor antagonists

1 reference

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5 June 2018

Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine—II. Effects of acute administration of 1-PP and long-term adminstration of tandospirone on noradrenergic neurotransmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

1-(2-Pyrimidinyl)-piperazine may alter the effects of the 5-HT1A agonists in the learned helplessness paradigm in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

5 June 2018

The effects of clonidine and yohimbine on human information processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1364998

18 August 2018

A double-blind, placebo-controlled study comparing the efficacy and safety of ipsapirone versus lorazepam in patients with generalized anxiety disorder: a prospective multicenter trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological evidence for the involvement of 1-(2-pyridinyl)-piperazine (1-PmP) in the interaction of buspirone or gepirone with noradrenergic systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alpha 2-adrenoceptor antagonist activity of ipsapirone and gepirone is mediated by their common metabolite 1-(2-pyrimidinyl)-piperazine (PmP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of buspirone, gepirone, ipsapirone and their common metabolite 1-(2-pyrimidinyl)piperazine in rat plasma and brain by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine responses to 5-hydroxytryptamine-1A receptor activation by ipsapirone in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that the 5-HT1A receptor agonists buspirone and ipsapirone activate adrenaline release in the conscious rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of MK-467, a peripheral α2-adrenergic receptor antagonist, with intravenous clonidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pindolol on endocrine and temperature responses to buspirone in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of buspirone on prolactin and growth hormone secretion in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/7619663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.1995.TB04443.X

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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