Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases (Q41527389)

2 October 2017

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title

Proposal for pharmacologically distinct conformers of PDE4 cyclic AMP phosphodiesterases (English)

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2 October 2017

Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases (English)

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https://api.crossref.org/works/10.1016/S0898-6568(96)00173-8

14 September 2024

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J. E. Souness

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9218122

14 September 2024

S. Rao

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9218122

14 September 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9218122

14 September 2024

publication date

1 May 1997

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full work available at URL

2 October 2017

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inferred from page(s)

https://api.elsevier.com/content/article/PII:S0898656896001738?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/S0898-6568(96)00173-8

https://api.elsevier.com/content/article/PII:S0898656896001738?httpAccept=text/plain

14 September 2024

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https://api.crossref.org/works/10.1016/S0898-6568(96)00173-8

14 September 2024

1 reference

2 October 2017

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2 October 2017

issue

3-4

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2 October 2017

page(s)

227-236

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Characterization of cAMP-dependent inhibition of LPS-induced TNF alpha production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor

2 October 2017

cites work

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7 January 2021

The specific type III and IV phosphodiesterase inhibitor zardaverine suppresses formation of tumor necrosis factor by macrophages

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7 January 2021

Tumor necrosis factor, other cytokines and disease

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7 January 2021

NIH conference. Immunopathogenic mechanisms in human immunodeficiency virus (HIV) infection

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7 January 2021

Anti-inflammatory activity of phosphodiesterase (PDE)-IV inhibitors in acute and chronic models of inflammation

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7 January 2021

Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor

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7 January 2021

The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis

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Excitation of area postrema neurons by transmitters, peptides, and cyclic nucleotides

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7 January 2021

Effect of the phosphodiesterase inhibitor 4-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone (ZK 62711) on gastric secretion and gastric mucosal cyclic AMP

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7 January 2021

Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret

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7 January 2021

The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors

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7 January 2021

Characterization of guinea-pig eosinophil phosphodiesterase activity. Assessment of its involvement in regulating superoxide generation

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7 January 2021

Engineered deletion of the unique N-terminal domain of the cyclic AMP-specific phosphodiesterase RD1 prevents plasma membrane association and the attainment of enhanced thermostability without altering its sensitivity to inhibition by rolipram

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7 January 2021

Stereospecificity of rolipram actions on eosinophil cyclic AMP-specific phosphodiesterase

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7 January 2021

Effects of solubilization and vanadate/glutathione complex on inhibitor potencies against eosinophil cyclic AMP-specific phosphodiesterase

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7 January 2021

Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP‐specific phosphodiesterase: comparison with rolipram

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7 January 2021

Molecular cloning and functional expression in yeast of a human cAMP-specific phosphodiesterase subtype (PDE IV-C).

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7 January 2021

A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs

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7 January 2021

The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4.

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7 January 2021

Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase

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7 January 2021

Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer

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7 January 2021

Association of the anti-inflammatory activity of phosphodiesterase 4 (PDE4) inhibitors with either inhibition of PDE4 catalytic activity or competition for [3H]rolipram binding

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7 January 2021

Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IVD)

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7 January 2021

Characterization of two human cAMP‐specific phosphodiesterase subtypes expressed in baculovirus‐infected insect cells

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7 January 2021

Stereospecific binding of the antidepressant rolipram to brain protein structures

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7 January 2021

Close correlation between behavioural response and binding in vivo for inhibitors of the rolipram-sensitive phosphodiesterase

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7 January 2021

Rolipram, a stereospecific inhibitor of calmodulin-independent phosphodiesterase, causes beta-adrenoceptor subsensitivity in rat cerebral cortex

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7 January 2021

Brain cAMP response to phosphodiesterase inhibitors in rats killed by microwave irradiation or decapitation

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7 January 2021

Unusual stereospecificity of the potential antidepressant rolipram on the cyclic AMP generating system from rat brain cortex

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7 January 2021

Research requires action

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7 January 2021

Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors

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7 January 2021

Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone

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7 January 2021

Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: a diverse family of regulatory enzymes

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7 January 2021

Expression and regulation of human and rat phosphodiesterase type IV isogenes

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7 January 2021

Type III cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE3 gene family)

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7 January 2021

Structure-activity relationship of quinazolinedione inhibitors of calcium-independent phosphodiesterase

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7 January 2021

Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase

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7 January 2021

The human cyclic AMP-specific phosphodiesterase PDE-46 (HSPDE4A4B) expressed in transfected COS7 cells occurs as both particulate and cytosolic species that exhibit distinct kinetics of inhibition by the antidepressant rolipram

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7 January 2021

Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases

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7 January 2021

Protein kinase recognition sequence motifs

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14 September 2024

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14 September 2024

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14 September 2024

Identifiers

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2 October 2017

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