Sodium 4-phenylbutyrate ameliorates the effects of cataract-causing mutant gammaD-crystallin in cultured cells. (Q41345156)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20577655%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Sodium 4-phenylbutyrate ameliorates the effects of cataract-causing mutant gammaD-crystallin in cultured cells (English)

1 reference

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6 February 2020

Gary Hin-Fai Yam

1 reference

29 September 2017

Dennis Shun-Chiu Lam

1 reference

29 September 2017

Bo Gong

1 reference

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6 February 2020

Li-Yun Zhang

1 reference

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6 February 2020

Chi-Pui Pang

1 reference

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6 February 2020

Dennis Shun-Chiu Lam

1 reference

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6 February 2020

Gary Hin-Fai Yam

1 reference

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6 February 2020

publication date

4 June 2010

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6 February 2020

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6 February 2020

volume

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6 February 2020

page(s)

997-1003

1 reference

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Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin

6 February 2020

cites work

1 reference

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A novel gammaD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract

1 October 2017

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The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response

1 October 2017

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The role of molecular chaperones in human misfolding diseases

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1 October 2017

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Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure

1 October 2017

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Protein misfolding in conformational disorders: rescue of folding defects and chemical chaperoning

1 October 2017

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Crystallin gene mutations in Indian families with inherited pediatric cataract

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state

1 October 2017

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Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

1 October 2017

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Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecule modulators

1 October 2017

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Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress

1 October 2017

1 reference

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Pharmacological chaperone corrects lysosomal storage in Fabry disease caused by trafficking-incompetent variants

1 October 2017

1 reference

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ERAD: the long road to destruction

1 October 2017

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Endoplasmic reticulum-associated protein degradation--one model fits all?

1 October 2017

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Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease

1 October 2017

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Heat shock protein 70 expression, keratin phosphorylation and Mallory body formation in hepatocytes from griseofulvin-intoxicated mice

1 October 2017

1 reference

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Chemical chaperones protect from effects of apoptosis-inducing mutation in carbonic anhydrase IV identified in retinitis pigmentosa 17.

1 October 2017

1 reference

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Defective trafficking of nephrin missense mutants rescued by a chemical chaperone

1 October 2017

1 reference

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The role of protein misfolding in the pathogenesis of human diseases.

1 October 2017

1 reference

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Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins

1 October 2017

1 reference

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Quality Control and Protein Folding in the Secretory Pathway

1 October 2017

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Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration

1 October 2017

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Quality control in the endoplasmic reticulum

1 October 2017

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1 October 2017

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1 October 2017

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Induction of HSP70 promotes DeltaF508 CFTR trafficking

1 October 2017

1 reference

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Sodium 4-phenylbutyrate downregulates HSC70 expression by facilitating mRNA degradation

1 October 2017

1 reference

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Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

1 October 2017

1 reference

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1 October 2017

1 reference

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1 October 2017

1 reference

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1 October 2017

1 reference

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Osmolyte-driven contraction of a random coil protein

1 October 2017

1 reference

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Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis

1 October 2017

1 reference

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Zebrafish Hsp70 is required for embryonic lens formation

11 June 2018

1 reference

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11 June 2018

1 reference

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Histone deacetylase inhibitor 4-phenylbutyrate modulates glial fibrillary acidic protein and connexin 43 expression, and enhances gap-junction communication, in human glioblastoma cells

11 June 2018

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11 June 2018

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11 June 2018

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19 August 2018

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Conformational disease

1 reference

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19 August 2018

1 reference

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12 December 2020

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A novel deletion variant of gammaD-crystallin responsible for congenital nuclear cataract

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20577655%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

20577655

1 reference

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