voriconazole (Q412236)

DrugBank

imported from Wikimedia project

17 November 2015

Voriconazole Structural Formula V.1.svg
339 × 444; 18 KB

1 reference

German Wikipedia

mass

349.115 dalton

1 reference

Voriconazole (English)

(2R,3R)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

19 October 2016

stereoisomer of

2 references

(2S,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1,2,4-triazol-1-yl)-2-butanol

1 reference

1 reference

inferred from InChI

chemical formula

C₁₆H₁₄F₃N₅O

1 reference

Voriconazole (English)

19 October 2016

canonical SMILES

CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O

1 reference

Voriconazole (English)

19 October 2016

isomeric SMILES

C[C@@H](C1=NC=NC=C1F)[C@](O)(CN2C=NC=N2)C3=CC=C(F)C=C3F

1 reference

European Medicines Agency product number

14 February 2018

1 reference

14 February 2018

1 reference

EMEA/H/C/002669

reference URL

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002669/human_med_001651.jsp

European Medicines Agency product number

22 March 2017

Voriconazole Hospira

1 reference

EMEA/H/C/003737

reference URL

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/003737/human_med_001866.jsp

World Health Organisation international non-proprietary name

22 March 2017

voriconazole (English)

1 reference

Polyhydroxy Cyclohexanols from a Dendrodochium sp. Fungus Associated with the Sea Cucumber Holothuria nobilis Selenka

voriconazole (English)

19 October 2016

1 reference

medical condition treated

2 references

13 December 2016

2 October 2018

fusariosis

1 reference

2 October 2018

candidiasis

1 reference

2 October 2018

systemic mycosis

1 reference

2 October 2018

lung disease

1 reference

2 October 2018

pneumonia

1 reference

Food and Drug Administration

2 October 2018

esophageal candidiasis

start time

8 December 2003

approved by

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/JFU09I87TR

2 November 2018

reference URL

http://www.accessdata.fda.gov/drugsatfda_docs/label/2003/021466lbl.pdf

significant drug interaction

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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LiverTox likelihood score

LiverTox toxicity likelihood category B

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Voriconazole

last update

17 May 2017

subject has role

cytochrome P-450 CYP3A inhibitors

1 reference

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D065819

14-alpha demethylase inhibitor

15 March 2018

1 reference

Medical Subject Headings

15 March 2018

0 references

C1707

1 reference

InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1

14 February 2018

Voriconazole

0 references

Identifiers

InChI

1 reference

Voriconazole (English)

19 October 2016

2 references

Voriconazole (English)

19 October 2016

14 February 2018

2 references

voriconazole (English)

19 October 2016

14 February 2018

1 reference

Voriconazole (English)

19 October 2016

2 references

Voriconazole (English)

19 October 2016

Reaxys registry number

7694998

1 reference

voriconazole (English)

19 October 2016

ChEBI ID

10023

mapping relation type

3 references

voriconazole (English)

19 October 2016

ChEBI release 2021-03-01

International Chemical Identifier

InChI

InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1

1 reference

VORICONAZOLE (English)

19 October 2016

2 references

splash10-0fh9-2593000000-630f0453fb0da8e2745d

1 reference

0 references

DSSTox substance ID

DTXSID5046485

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.157.870

27 December 2018

ECHA Substance Infocard ID

(2R, 3S)-2-(2, 4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1, 2, 4-triazol-1-yl)butan-2-ol (English)

quotation

CAS no.: 137234-62-9 (English)

100.157.870

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.157.870

27 December 2018

(2R, 3S)-2-(2, 4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1, 2, 4-triazol-1-yl)butan-2-ol (English)

quotation

CAS no.: 137234-62-9 (English)

1 reference

Voriconazole (English)

17 November 2015

Voriconazole

0 references

0 references

0 references

1 reference

14 February 2018

1 reference

Human Metabolome Database ID

HMDB0014720

2 references

KNApSAcK ID

C00059772

2 references

3 references

Voriconazole (English)

19 October 2016

UNII

JFU09I87TR

14 February 2018

USG4B1CD29

1 reference

MedlinePlus drug identifier

a605022

0 references

PatientsLikeMe treatment ID

0 references

1 reference

VORICONAZOLE (English)

19 January 2016

0 references

1 reference

1 reference

voriconazole (English)

19 October 2016

1 reference

electronic Essential Medicines List medicine ID

voriconazole (English)

19 October 2016

0 references

1 reference

6 April 2020

0 references

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

3MDT (English)

19 October 2016

1 reference

4ZE0 (English)

19 October 2016

1 reference

4UYM (English)

19 October 2016

1 reference