2-chloro-2'-deoxyadenosine: clinical applications in hematology (Q41227738)

28 September 2017

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title

2-chloro-2'-deoxyadenosine: clinical applications in hematology (English)

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28 September 2017

Delannoy A

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28 September 2017

publication date

1 September 1996

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

page(s)

148-166

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2-Chlorodeoxyadenosine (2-CdA): A Potent Chemotherapeutic and Immunosuppressive Nucleoside

28 September 2017

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7 January 2021

Lasting remissions in hairy-cell leukemia induced by a single infusion of 2-chlorodeoxyadenosine

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7 January 2021

2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies

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7 January 2021

Clinical and toxicological aspects of the antineoplastic drug cladribine: a review

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7 January 2021

Cladribine (2-chlorodeoxyadenosine)

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Cladribine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in haematological malignancies

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Purine analogs in the treatment of low-grade lymphomas and chronic lymphocytic leukemias

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7 January 2021

Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukaemic patients

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7 January 2021

2-Chlorodeoxyadenosine dose escalation in nonhematologic malignancies

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7 January 2021

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes

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7 January 2021

Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy

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Protein binding of 2-chloro 2'-deoxyadenosine (cladribine) in healthy subjects and in patients with leukaemia

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7 January 2021

Renal handling of 2'-deoxyadenosine and adenosine in humans and mice

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7 January 2021

On the bioavailability of oral and subcutaneous 2-chloro-2'-deoxyadenosine in humans: alternative routes of administration

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7 January 2021

2-Chlorodeoxyadenosine Treatment of Refractory Chronic Lymphocytic Leukemia

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7 January 2021

Pharmacokinetic study of oral and bolus intravenous 2-chlorodeoxyadenosine in patients with malignancy

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7 January 2021

A phase I and pharmacokinetics study of 2-chlorodeoxyadenosine in patients with solid tumors

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7 January 2021

Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma

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7 January 2021

A phase I clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia

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7 January 2021

A phase I study of intermittent infusion cladribine in patients with solid tumors

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7 January 2021

Low-dose cladribine for symptomatic hairy cell leukaemia

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7 January 2021

High incidence of infections after 2-chlorodeoxyadenosine (2-CDA) therapy in patients with malignant lymphomas and chronic and acute leukaemias

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7 January 2021

Treatment of Waldenstrom's macroglobulinemia resistant to standard therapy with 2-chlorodeoxyadenosine: identification of prognostic factors

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7 January 2021

Subcutaneous injections of 2-chlorodeoxyadenosine for symptomatic hairy cell leukemia

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7 January 2021

Cladribine in the treatment of relapsed or refractory chronic lymphocytic leukemia

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7 January 2021

2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia

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7 January 2021

Neurotoxicity of purine analogs: a review

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7 January 2021

Marrow suppression produced by repeated doses of cladribine

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7 January 2021

Cladribine and severe myelotoxicity

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7 January 2021

Neutropenic fever following cladribine therapy for symptomatic hairy-cell leukemia: predictive factors and effects of granulocyte-macrophage colony-stimulating factor

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7 January 2021

Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy

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7 January 2021

Acute onset of severe autoimmune hemolytic anemia after treatment with 2-chlorodeoxyadenosine for chronic lymphocytic leukemia

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7 January 2021

Transfusion-associated graft-versus-host disease in a patient treated with Cladribine (2-chlorodeoxyadenosine): demonstration of exogenous DNA in various tissue extracts by PCR analysis

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7 January 2021

High complete remission rate from 2-chloro-2'-deoxyadenosine in previously treated patients with B-cell chronic lymphocytic leukemia: response predicted by rapid decrease of blood lymphocyte count

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7 January 2021

Cladribine in treatment of chronic progressive multiple sclerosis

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7 January 2021

2-Chlorodeoxyadenosine in the treatment of hairy cell leukemia and chronic lymphocytic leukemia

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7 January 2021

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7 January 2021

High complete remission rate in hairy cell leukemia treated with 2-chlorodeoxyadenosine

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7 January 2021

Complete remissions in hairy cell leukemia with 2-chlorodeoxyadenosine after failure with 2'-deoxycoformycin

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7 January 2021

Minimal residual disease in hairy-cell leukemia after treatment with 2-chlorodeoxyadenosine

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7 January 2021

Long-term survival following cladribine (2-chlorodeoxyadenosine) therapy in previously treated patients with chronic lymphocytic leukemia

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7 January 2021

Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine

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7 January 2021

2-Chlorodeoxyadenosine for patients with B-cell chronic lymphocytic leukemia resistant to fludarabine

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7 January 2021

Care of patients with ascites

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7 January 2021

Brief report: tumor lysis syndrome following treatment with 2-chlorodeoxyadenosine for refractory chronic lymphocytic leukemia

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7 January 2021

Treatment of advanced chronic lymphocytic leukemia by fludarabine

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7 January 2021

A loading dose/continuous infusion schedule of fludarabine phosphate in chronic lymphocytic leukemia

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7 January 2021

Immunosuppressive effects and clinical response of fludarabine in refractory chronic lymphocytic leukemia

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7 January 2021

Retreatment of chronic lymphocytic leukemia with 2-chlorodeoxyadenosine (CdA) at relapse following CdA-induced remission: no acquired resistance

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7 January 2021

Guidelines for clinical protocols for chronic lymphocytic leukemia: recommendations of the National Cancer Institute-sponsored working group

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7 January 2021

Molecular Complete Response in a Patient with Chronic Lymphocytic Leukaemia Treated with 2-Chlorodeoxyadenosine

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7 January 2021

Primary therapy of Waldenström's macroglobulinemia with 2-chlorodeoxyadenosine

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7 January 2021

Treatment of Waldenstrom's Macroglobulinemia with Nucleoside Analogues

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7 January 2021

2Chlorodeoxyadenosine therapy of patients with Waldenström macroglobulinemia previously treated with fludarabine

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7 January 2021

2'-Chlorodeoxyadenosine: evaluation of a novel predominantly lymphocyte selective agent in lymphoid malignancies

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7 January 2021

2-Chlorodeoxyadenosine treatment of low-grade lymphomas

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7 January 2021

2-Chlorodeoxyadenosine is an active salvage therapy in advanced indolent non-Hodgkin's lymphoma

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7 January 2021

Follicular non-Hodgkin's lymphoma

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7 January 2021

2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms

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7 January 2021

2-Chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia

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7 January 2021

Principal results of the Medical Research Council's 8th acute myeloid leukaemia trial

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7 January 2021

2-Chlorodeoxyadenosine and multiple myeloma

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7 January 2021

Complete hematologic remissions in chronic-phase, Philadelphia-chromosome-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine

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7 January 2021

2-Chlorodeoxyadenosine to treat refractory histiocytosis X.

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7 January 2021

2-Chlorodeoxyadenosine-induced complete remissions in Langerhans-cell histiocytosis.

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7 January 2021

Complete remission in T-cell prolymphocytic leukemia with 2-chlorodeoxyadenosine

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7 January 2021

Rapid response of B-cell prolymphocytic leukemia to 2-chlorodeoxyadenosine

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7 January 2021

2-Chloro-deoxyadenosine therapy for giant lymph node hyperplasia

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7 January 2021

10.1016/S0268-960X(96)90022-3

Identifiers

DOI

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28 September 2017

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