mTOR Inhibitor Treatment of Pancreatic Cancer in a Patient With Peutz-Jeghers Syndrome (Q40972751)

25 September 2017

mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome (English)

1 reference

25 September 2017

mTOR Inhibitor Treatment of Pancreatic Cancer in a Patient With Peutz-Jeghers Syndrome (English)

1 reference

Crossref

DOI

10.1200/JCO.2010.32.7825

https://api.crossref.org/works/10.1200/JCO.2010.32.7825

20 November 2024

1 reference

Peutz-Jeghers syndrome

1 reference

1 reference

C. Arnold Spek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

20 November 2024

Heinz-Josef Klümpen

1 reference

25 September 2017

Karla C. S. Queiroz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

20 November 2024

Carel J. M. van Noesel

1 reference

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20 November 2024

Helmy C. Brink

1 reference

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20 November 2024

Wendy W. J. de Leng

1 reference

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20 November 2024

Roeland F. de Wilde

1 reference

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20 November 2024

Elisabeth M. H. Mathus-Vliegen

1 reference

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20 November 2024

G. Johan A. Offerhaus

1 reference

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20 November 2024

Maarten A. Alleman

1 reference

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20 November 2024

Anneke M. Westermann

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

20 November 2024

Dirk J. Richel

1 reference

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20 November 2024

language of work or name

English

0 references

publication date

28 December 2010

1 reference

full work available at URL

25 September 2017

https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2010.32.7825?role=tab

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

http://intl.jco.org/cgi/content/abstract/29/6/e150

20 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

https://europepmc.org/articles/PMC4856022

20 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

https://europepmc.org/articles/PMC4856022?pdf=render

20 November 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

https://doi.org/10.1200/jco.2010.32.7825

20 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21189378

https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2010.32.7825

20 November 2024

1 reference

Crossref

DOI

10.1200/JCO.2010.32.7825

https://api.crossref.org/works/10.1200/JCO.2010.32.7825

Journal of Clinical Oncology

20 November 2024

published in

1 reference

25 September 2017

1 reference

25 September 2017

1 reference

25 September 2017

e150-3

1 reference

LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

High cancer risk in Peutz-Jeghers syndrome: a systematic review and surveillance recommendations

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

LKB1; linking cell structure and tumor suppression

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Defining the role of mTOR in cancer

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Very high risk of cancer in familial Peutz-Jeghers syndrome

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4856022

19 August 2018

Identifiers

DOI

10.1200/JCO.2010.32.7825

1 reference

25 September 2017

1 reference

25 September 2017

1 reference