Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells (Q40940916)

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scientific article published on August 1999

Language	Label	Description	Also known as
English	Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells	scientific article published on August 1999

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

colorectal cancer

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based on heuristic

inferred from title

author name string

Vahrmeijer AL

1

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Europe PubMed Central

PubMed publication ID

25 September 2017

van Dierendonck JH

2

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Europe PubMed Central

PubMed publication ID

25 September 2017

Schutrups J

3

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Europe PubMed Central

PubMed publication ID

25 September 2017

van de Velde CJ

4

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Europe PubMed Central

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25 September 2017

Mulder GJ

5

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Europe PubMed Central

PubMed publication ID

25 September 2017

language of work or name

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publication date

1 August 1999

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Europe PubMed Central

PubMed publication ID

25 September 2017

Biochemical Pharmacology

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PubMed publication ID

25 September 2017

58

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Europe PubMed Central

PubMed publication ID

25 September 2017

4

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25 September 2017

655-664

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Europe PubMed Central

PubMed publication ID

25 September 2017

Glutathione: toxicological implications

1 reference

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7 January 2021

Recent Trends in Glutathione Biochemistry—Glutathione–Protein Interactions: A Molecular Link between Oxidative Stress and Cell Proliferation?

1 reference

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Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death

1 reference

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Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione

1 reference

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Reduction in glutathione content of L-PAM resistant L1210 Cells confers drug sensitivity.

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Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

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Membrane transport, sulfhydryl levels and DNA cross-linking in Chinese hamster ovary cell mutants sensitive and resistant to melphalan.

1 reference

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Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2.

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Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells

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Apoptotic death in an in vitro model of neuronal oxidative stress

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Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

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Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution

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The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

1 reference

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7 January 2021

Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites.

1 reference

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7 January 2021

Rescue of cells from apoptosis by inhibition of active GSH extrusion.

1 reference

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7 January 2021

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease

1 reference

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7 January 2021

Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

1 reference

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Energy supply and the shape of death in neurons and lymphoid cells

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Apoptosis and necrosis: intracellular ATP level as a determinant for cell death modes

1 reference

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7 January 2021

Tissue sulfhydryl groups

1 reference

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Glutathione conjugation of bromosulfophthalein in relation to hepatic glutathione content in the rat in vivo and in the perfused rat liver

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7 January 2021

Chemosensitivity testing of human lung cancer cell lines using the MTT assay

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A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

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7 January 2021

Hydrolysis and Protein Binding of Melphalan

1 reference

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The relationship between intracellular Ca2+ and the mitochondrial membrane potential in isolated proximal tubular cells from rat kidney exposed to the nephrotoxin 1,2-dichlorovinyl-cysteine

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7 January 2021

Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in chinese hamster ovary cell cultures treated with cisplatin

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7 January 2021

Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.

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7 January 2021

Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells

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Enhanced host cell reactivation capacity and expression of DNA repair genes in human breast cancer cells resistant to bi-functional alkylating agents

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7 January 2021

Bcl-2 expression causes redistribution of glutathione to the nucleus

1 reference

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7 January 2021

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

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7 January 2021

Mitochondrial control of apoptosis

1 reference

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7 January 2021

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

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Hepatocyte toxicity of mechlorethamine and other alkylating anticancer drugs. Role of lipid peroxidation

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7 January 2021

Identifiers

10.1016/S0006-2952(99)00130-6

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

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