The future of new pure antiestrogens in clinical breast cancer (Q40920558)

24 September 2017

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title

The future of new pure antiestrogens in clinical breast cancer (English)

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24 September 2017

A E Wakeling

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24 September 2017

language of work or name

English

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publication date

1 January 1993

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Breast Cancer Research and Treatment

24 September 2017

published in

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

1-9

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Adjuvant tamoxifen for early breast cancer

24 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FBF00662395

Comparative studies on the effects of steroidal and nonsteroidal oestrogen antagonists on the proliferation of human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00662395

Examination of the DNA-binding ability of estrogen receptor in whole cells: implications for hormone-independent transactivation and the actions of antiestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00662395

Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00662395

Indirect mechanism of oestradiol stimulation of cell proliferation of human breast cancer cell lines

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF00662395

The pharmacology and clinical uses of tamoxifen

21 January 2018

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12 December 2020

Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo.

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12 December 2020

Heterogeneity of progesterone receptor content and remodeling by tamoxifen characterize subpopulations of cultured human breast cancer cells: analysis by quantitative dual parameter flow cytometry

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12 December 2020

Comparison of the biological effects of tamoxifen and a new antioestrogen (LY 117018) on the immature rat uterus

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12 December 2020

Response after withdrawal of tamoxifen and progestogens in advanced breast cancer

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12 December 2020

Potential role of tamoxifen in prevention of breast cancer

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12 December 2020

Antiuterotrophic effects of a pure antioestrogen, ICI 182,780: magnetic resonance imaging of the uterus in ovariectomized monkeys

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12 December 2020

Actions of oestrogens and antioestrogens on rat mammary gland development: relevance to breast cancer prevention

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12 December 2020

Identification of estrogenic tamoxifen metabolite(s) in tamoxifen-resistant human breast tumors

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12 December 2020

Effect of estrogen and antiestrogens on cell proliferation and synthesis of secreted proteins in the human breast cancer cell line MCF-7 and a tamoxifen resistant variant subline, AL-1.

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12 December 2020

Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration

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Prevention of breast cancer with tamoxifen--an update on the Royal Marsden Hospital pilot programme

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12 December 2020

Steroidal pure antioestrogens

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12 December 2020

Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group

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Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover

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12 December 2020

Estrogen deprivation in breast cancer. Clinical, experimental, and biological aspects

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12 December 2020

Tamoxifen and the isomers of 4-hydroxytamoxifen in tamoxifen-resistant tumors from breast cancer patients

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12 December 2020

Endocrine pharmacology of antiestrogens as antitumor agents

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12 December 2020

Novel steroidal pure antiestrogens

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12 December 2020

Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.

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12 December 2020

The mechanism of ICI 164,384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissue

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Steroid antagonists as nuclear receptor blockers

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12 December 2020

Therapeutic potential of pure antioestrogens in the treatment of breast cancer

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12 December 2020

Contrasting Endocrine Activities of cis and trans Isomers in a Series of Substituted Triphenylethylenes

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12 December 2020

ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness.

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12 December 2020

Adjuvant tamoxifen in early breast cancer: occurrence of new primary cancers

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12 December 2020

Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization

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12 December 2020

Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen.

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12 December 2020

Antioestrogens in the management of hormone-dependent cancer

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12 December 2020

Human breast cancer in the athymic nude mouse: cytostatic effects of long-term antiestrogen therapy

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12 December 2020

A new derivative of triphenylethylene: effect on implantation and mode of action in rats

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12 December 2020

A potent specific pure antiestrogen with clinical potential

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12 December 2020

Points of action of estrogen antagonists and a calmodulin antagonist within the MCF-7 human breast cancer cell cycle.

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12 December 2020

Effects of antioestrogens on the proliferation of MCF-7 human breast cancer cells

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12 December 2020

Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells

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12 December 2020

Novel antioestrogens without partial agonist activity

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12 December 2020

Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment.

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12 December 2020

Identifiers

DOI

10.1007/BF00662395

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Dimensions Publication ID

24 September 2017

1002049364

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