Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts (Q40891235)

24 September 2017

title

Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts (English)

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24 September 2017

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S Plyte

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24 September 2017

M B Majolini

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24 September 2017

S Pacini

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24 September 2017

F Scarpini

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24 September 2017

C Bianchini

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24 September 2017

L Lanfrancone

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24 September 2017

P Pelicci

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24 September 2017

C T Baldari

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24 September 2017

language of work or name

English

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publication date

1 March 2000

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

1529-1537

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Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

24 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Lymphocyte antigen receptor signal integration and regulation by the SHC adaptor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

The role of the PH domain in the signal-dependent membrane targeting of Sos.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Signal transmission between the plasma membrane and nucleus of T lymphocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Signal transduction in T lymphocytes using a conditional allele of Sos

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

The role of Grb2-associated proteins in T-cell activation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

New insights into the interaction of Ras with the plasma membrane

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Signal transduction. How receptors turn Ras on.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Tyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Protein modules and signalling networks

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Adaptor proteins in lymphocyte antigen-receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Evidence for a Requirement for Both Phospholipid and Phosphotyrosine Binding via the Shc Phosphotyrosine-Binding Domain In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Adaptors and molecular scaffolds in immune cell signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Functional rafts in cell membranes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Membrane compartmentation is required for efficient T cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203451

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203451

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Dimensions Publication ID

24 September 2017

1027887006

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