IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation (Q40874616)

24 September 2017

title

IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation (English)

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24 September 2017

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K Reiss

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24 September 2017

J Y Wang

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24 September 2017

G Romano

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24 September 2017

F B Furnari

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24 September 2017

W K Cavenee

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24 September 2017

A Morrione

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24 September 2017

X Tu

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24 September 2017

R Baserga

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24 September 2017

language of work or name

English

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publication date

1 May 2000

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

2687-2694

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Autocrine regulation of cell proliferation by the insulin-like growth factor (IGF) and IGF binding protein-3 protease system in a human prostate carcinoma cell line (PC-3).

24 September 2017

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Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

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Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts

21 January 2018

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Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

21 January 2018

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Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor

21 January 2018

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

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Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia

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The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling

21 January 2018

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Role of binding proteins to IRS-1 in insulin signalling

21 January 2018

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Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

21 January 2018

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Reexpression of the type 1 insulin-like growth factor receptor inhibits the malignant phenotype of simian virus 40 T antigen immortalized human prostate epithelial cells

21 January 2018

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Synthetic peptide sequence from the C-terminus of the insulin-like growth factor-I receptor that induces apoptosis and inhibition of tumor growth

21 January 2018

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Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling.

21 January 2018

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

21 January 2018

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

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PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

21 January 2018

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Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules

21 January 2018

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Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion

21 January 2018

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PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.

21 January 2018

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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

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Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

21 January 2018

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Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes

21 January 2018

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7 January 2021

Cross-talk between insulin receptor and integrin alpha5 beta1 signaling pathways

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7 January 2021

Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells

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7 January 2021

Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203587

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Dimensions Publication ID

24 September 2017

1045386828

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1 reference