E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells (Q40869804)

24 September 2017

title

E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells (English)

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24 September 2017

W J Romanow

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24 September 2017

A W Langerak

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24 September 2017

P Goebel

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24 September 2017

I L Wolvers-Tettero

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24 September 2017

J J van Dongen

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24 September 2017

A J Feeney

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24 September 2017

C Murre

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24 September 2017

publication date

1 February 2000

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

343-353

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Early B-cell factor (EBF) down-regulates immunoglobulin heavy chain intron enhancer function in a plasmacytoma cell line

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Positive and negative regulation of V(D)J recombination by the E2A proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Conserved sequence elements in K promoters from mice and humans: implications for transcriptional regulation and repertoire expression

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

E47 activates the Ig-heavy chain and TdT loci in non-B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

A directory of human germ-line V kappa segments reveals a strong bias in their usage

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Failure of B-cell differentiation in mice lacking the transcription factor EBF.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Complementation of V(D)J Recombination Deficiency in RAG-1−/− B Cells Reveals a Requirement for Novel Elements in the N-Terminus of RAG-1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

The V(D)J recombination activating gene, RAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

B-cell-specific DNA binding by an E47 homodimer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Immunoglobulin kappa light chain germ-line transcripts in human precursor B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Initiation of V(D)J recombination in a cell-free system.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

The helix-loop-helix gene E2A is required for B cell formation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980429-3

7 January 2021

10.1016/S1097-2765(00)80429-3

Identifiers

DOI

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24 September 2017

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