A challenge to the instructive model of positive selection (Q40801692)

23 September 2017

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title

A challenge to the instructive model of positive selection (English)

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23 September 2017

Chan SH

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23 September 2017

Benoist C

series ordinal

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23 September 2017

Mathis D

series ordinal

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23 September 2017

language of work or name

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1 October 1993

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23 September 2017

published in

Immunological Reviews

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23 September 2017

volume

135

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23 September 2017

page(s)

119-131

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MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Activation events during thymic selection

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Positive selection of the T cell repertoire: where and when does it occur?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

The effects of MHC gene dosage and allelic variation on T cell receptor selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Inefficient positive selection of T cells directed by haematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Cytotoxic T lymphocyte responses in allogeneic radiation bone marrow chimeras. The chimeric host strictly dictates the self-repertoire of Ia-restricted T cells but not H-2K/D-restricted T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Another view of the selective model of thymocyte selection

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Mice lacking MHC class II molecules

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Making a difference: the role of cell-cell interactions in establishing separate identities for equivalent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

A cell line that can induce thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Self-recognition specificity expressed by T cells from nude mice. Absence of detectable Ia-restricted T cells in nude mice that do exhibit self-K/D-restricted T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Mice lacking the MHC class II-associated invariant chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

The selection of the α,β heterodimeric T-cell receptor for antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Subpopulations of mature murine thymocytes: properties of CD4-CD8+ and CD4+CD8- thymocytes lacking the heat-stable antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Accessories or coreceptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Participation of CD4 coreceptor molecules in T-cell repertoire selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1993.TB00646.X

10.1111/J.1600-065X.1993.TB00646.X

21 January 2018

Identifiers

DOI

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23 September 2017

1 reference