Formation, detection, and role in carcinogenesis of ethenobases in DNA. (Q40700878)

22 September 2017

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title

Formation, detection, and role in carcinogenesis of ethenobases in DNA. (English)

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22 September 2017

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Bartsch H

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22 September 2017

Barbin A

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22 September 2017

Marion MJ

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22 September 2017

Nair J

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22 September 2017

Guichard Y

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22 September 2017

language of work or name

English

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publication date

1 January 1994

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22 September 2017

published in

Drug Metabolism Reviews

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22 September 2017

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22 September 2017

issue

1-2

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22 September 2017

page(s)

349-371

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Ethyl carbamate: analytical methodology, occurrence, formation, biological activity and risk assessment

22 September 2017

cites work

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The Need for Epidemiological Studies of the Medical Exposures of Japanese Patients to the Carcinogen Ethyl Carhamate (Urethane) from 1950 to 1975

21 January 2018

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Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

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Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolites in vitro and in vivo

21 January 2018

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Alkylation of RNA by vinyl bromide metabolites in vitro and in vivo

21 January 2018

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Alkylation of DNA and proteins in mice exposed to vinyl chloride

21 January 2018

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Interactions of vinyl chloride with rat-liver DNA in vivo

21 January 2018

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1,N6-etheno-2'-deoxyadenosine and 3,N4-etheno-2'-deoxycytidine detected by monoclonal antibodies in lung and liver DNA of rats exposed to vinyl chloride.

21 January 2018

1 reference

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Investigations on the relationship between DNA ethenobase adduct levels in several organs of vinyl chloride-exposed rats and cancer susceptibility

21 January 2018

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Vinyl chloride-induced DNA adducts. I: Quantitative determination of N2,3-ethenoguanine based on electrophore labeling

21 January 2018

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Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA.

21 January 2018

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Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver

21 January 2018

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Labeled 1,N6-ethenoadenosine and 3,N4-ethenocytidine in hepatic RNA of mice given[ethyl-1,2(-3)H or ethyl-1(-14)C]ethyl carbamate (urethan).

21 January 2018

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Alkylation of protein and DNA in mice treated with urethane

21 January 2018

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Enzymatic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadenosine

21 January 2018

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1,N6 formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate

21 January 2018

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Synthesis and properties of vinyl carbamate epoxide, a possible ultimate electrophilic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate

21 January 2018

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1,N2-ethenodeoxyguanosine: properties and formation in chloroacetaldehyde-treated polynucleotides and DNA

21 January 2018

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Nucleophilic selectivity as a determinant of carcinogenic potency (TD50) in rodents: a comparison of mono- and bi-functional alkylating agents and vinyl chloride metabolites

21 January 2018

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Fluorometric assay using high-pressure liquid chromatography for the microsomal metabolism of certain substituted aliphatics to 1,N6-ethenoadenine-forming metabolites.

21 January 2018

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Formation of 3,N4-ethenocytidine, 1,N6-ethenoadenosine, and 1,N2-ethenoguanosine in reactions of mucochloric acid with nucleosides

21 January 2018

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Quantitative and kinetic examination of 32P-postlabeling of etheno-substituted nucleotides.

21 January 2018

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Studies on the miscoding properties of 1,N6-ethenoadenine and 3,N4-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis

21 January 2018

1 reference

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Transcriptional errors and ambiguity resulting from the presence of 1,N6-ethenoadenosine or 3,N4-ethenocytidine in polyribonucleotides

21 January 2018

1 reference

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The vinyl chloride-derived nucleoside, N2,3-ethenoguanosine, is a highly efficient mutagen in transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli

21 January 2018

1 reference

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Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay

21 January 2018

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Assessment of mutagenic efficiency of two carcinogen-modified nucleosides, 1,N6-ethenodeoxyadenosine and O4-methyldeoxythymidine, using polymerases of varying fidelity

21 January 2018

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Miscoding potential of N2,3-ethenoguanine studied in an Escherichia coli DNA-dependent RNA polymerase in vitro system and possible role of this adduct in vinyl chloride-induced mutagenesis.

21 January 2018

1 reference

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NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite thymidine in a DNA duplex. Nonplanar alignment of epsilon dA(anti) and dT(anti) at the lesion site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite deoxyguanosine in a DNA duplex. Epsilon dA(syn).dG(anti) pairing at the lesion site

21 January 2018

1 reference

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Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Release of N2,3-ethenoguanine from chloroacetaldehyde-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase II

21 January 2018

1 reference

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Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane

21 January 2018

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Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors

21 January 2018

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Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse

21 January 2018

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Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

21 January 2018

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Genetic alterations in the 61st codon of the H-ras oncogene isolated from archival sections of hepatic hyperplasias, adenomas and carcinomas in control groups of B6C3F1 mouse bioassay studies conducted from 1979 to 1986

21 January 2018

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Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas

21 January 2018

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Comparison of Ki-ras gene mutation among simultaneously occurring multiple urethan-induced lung tumors in individual mice

21 January 2018

1 reference

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Multiple molecular alterations in mouse lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids

21 January 2018

1 reference

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10.3109/03602539409029802

21 January 2018

Identifiers

DOI

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22 September 2017

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