Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha). (Q40637524)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha) (English)

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7 November 2019

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7 November 2019

Wenling Chen

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7 November 2019

language of work or name

English

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publication date

1 August 2003

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7 November 2019

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7 November 2019

volume

313

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7 November 2019

page(s)

71-82

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Different effects on the expression of CYP7 and CYP27 in rabbit liver by cholic acid and cholestyramine.

7 November 2019

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Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport

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Removal of cholesterol from extrahepatic sources by oxidative mechanisms

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Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1

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7 January 2021

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

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Regulation of bile acid synthesis

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Bile acid regulation of gene expression: roles of nuclear hormone receptors.

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Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription

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7 January 2021

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

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7 January 2021

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

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Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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7 January 2021

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

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7 January 2021

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

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Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin

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7 January 2021

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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7 January 2021

Identification of a nuclear receptor for bile acids

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7 January 2021

Vitamin D receptor as an intestinal bile acid sensor

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In vivo and in vitro regulation of sterol 27-hydroxylase in the liver during the acute phase response. potential role of hepatocyte nuclear factor-1.

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7 January 2021

Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase

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7 January 2021

Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements.

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Bile acids: natural ligands for an orphan nuclear receptor

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Down-regulation of the rat hepatic sterol 27-hydroxylase gene by bile acids in transfected primary hepatocytes: possible role of hepatic nuclear factor 1alpha

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7 January 2021

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

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7 January 2021

Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene

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7 January 2021

Transcriptional regulation of the human sterol 27-hydroxylase gene (CYP27) and promoter mapping

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7 January 2021

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

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7 January 2021

Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes

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7 January 2021

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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7 January 2021

Redundant pathways for negative feedback regulation of bile acid production

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7 January 2021

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

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7 January 2021

Increasing dietary cholesterol induces different regulation of classic and alternative bile acid synthesis

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7 January 2021

On the mechanism of bile acid inhibition of rat sterol 12α-hydroxylase gene (CYP8B1) transcription: roles of α-fetoprotein transcription factor and hepatocyte nuclear factor 4α

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7 January 2021

Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression

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7 January 2021

10.1016/S0378-1119(03)00631-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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