Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice. (Q40468947)

20 September 2017

Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice. (English)

1 reference

20 September 2017

Victoria E H Wang

1 reference

20 September 2017

Tara Schmidt

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20 September 2017

Jianzhu Chen

1 reference

20 September 2017

Phillip A Sharp

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20 September 2017

Dean Tantin

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20 September 2017

language of work or name

English

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publication date

1 February 2004

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Molecular and Cellular Biology

20 September 2017

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20 September 2017

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20 September 2017

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20 September 2017

1022-1032

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describes a project that uses

20 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC321444/fullTextXML

inferred from PubMed Central ID database lookup

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CD3 zeta/eta/theta locus is colinear with and transcribed antisense to the gene encoding the transcription factor Oct-1.

22 September 2017

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Chromosomal structure and expression of the human OTF1 locus encoding the Oct-1 protein

22 September 2017

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Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

22 September 2017

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Targeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strand

22 September 2017

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Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse

22 September 2017

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Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival

22 September 2017

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Positive and negative regulation of IL-2 gene expression: role of multiple regulatory sites

22 September 2017

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Octamer factors exert a dual effect on the IL-2 and IL-4 promoters

22 September 2017

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OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

22 September 2017

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A B-cell coactivator of octamer-binding transcription factors

22 September 2017

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Cloning, sequencing and expression of two isoforms of the murine oct-1 transcription factor

22 September 2017

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Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B

22 September 2017

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Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2.

22 September 2017

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

22 September 2017

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Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence

22 September 2017

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Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes

22 September 2017

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The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains

22 September 2017

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The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products

22 September 2017

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The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2.

22 September 2017

1 reference

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

22 September 2017

1 reference

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Identification of sites for distinct DNA binding proteins including Oct-1 and Oct-2 in the Cr2 gene

22 September 2017

1 reference

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Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia

22 September 2017

1 reference

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Tissue-specific isoforms of the ubiquitous transcription factor Oct-1.

22 September 2017

1 reference

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Sequence-specific DNA binding of the B-cell-specific coactivator OCA-B.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321444

Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321444

Identification of an octamer element required for in vivo expression of the TIE1 gene in endothelial cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321444

Expression of novel alternatively spliced isoforms of the oct-1 transcription factor

17 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321444

Cloning and analysis of the human Pax-5 gene promoter

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321444

Cell type- and stage-specific expression of the CD20/B1 antigen correlates with the activity of a diverged octamer DNA motif present in its promoter

17 June 2018

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Transcription of a gene for human U1 small nuclear RNA.

17 June 2018

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Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.

17 June 2018

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Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities

17 June 2018

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The DNA binding specificity of the bipartite POU domain and its subdomains

17 June 2018

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LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of beta -globin intron-2.

17 June 2018

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Transcription factors Oct-1 and NF-YA regulate the p53-independent induction of the GADD45 following DNA damage

20 August 2018

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Transcriptional regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions.

20 August 2018

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Locus control region activity by 5'HS3 requires a functional interaction with beta-globin gene regulatory elements: expression of novel beta/gamma-globin hybrid transgenes

20 August 2018

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POU domain family values: flexibility, partnerships, and developmental codes

20 August 2018

1 reference

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A mouse model for β-thalassemia

20 August 2018

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12 December 2020

The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes

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12 December 2020

Involvement of the Oct-1 regulatory element of the gadd45 promoter in the p53-independent response to ultraviolet irradiation

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12 December 2020

The specific activation of gadd45 following UVB radiation requires the POU family gene product N-oct3 in human melanoma cells

1 reference

12 December 2020

B lymphocytes are impaired in mice lacking the transcriptional co-activator Bob1/OCA-B/OBF1

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12 December 2020

Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells

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12 December 2020

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

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12 December 2020

Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence

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12 December 2020

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

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12 December 2020

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

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12 December 2020

Binding of transcription factors to the promoter of the human U1 RNA gene studied by footprinting

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12 December 2020

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

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12 December 2020

The POU domain is a bipartite DNA-binding structure

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12 December 2020

10.1128/MCB.24.3.1022-1032.2004

Identifiers

DOI

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

14729950

1 reference