Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx. (Q40444273)

20 September 2017

title

Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx. (English)

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20 September 2017

main subject

photoreceptor protein

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author name string

Leonid E Lerner

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20 September 2017

Guang-Hua Peng

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20 September 2017

Yekaterina E Gribanova

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20 September 2017

Shiming Chen

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20 September 2017

Debora B Farber

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20 September 2017

language of work or name

English

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publication date

21 March 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

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20 September 2017

page(s)

20642-20650

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Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

20 September 2017

cites work

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The beta subunit of cyclic GMP phosphodiesterase mRNA is deficient in canine rod-cone dysplasia 1

21 January 2018

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Identification of genes causing photoreceptor degenerations leading to blindness

21 January 2018

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A point mutation of the rhodopsin gene in one form of retinitis pigmentosa

21 January 2018

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Rhodopsin mutations in autosomal dominant retinitis pigmentosa

21 January 2018

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Nrl and Sp nuclear proteins mediate transcription of rod-specific cGMP-phosphodiesterase beta-subunit gene: involvement of multiple response elements

21 January 2018

1 reference

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Crx, a Novel Otx-like Paired-Homeodomain Protein, Binds to and Transactivates Photoreceptor Cell-Specific Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500957200

Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500957200

Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx.

21 January 2018

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Retinopathy and attenuated circadian entrainment in Crx-deficient mice.

21 January 2018

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Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development

21 January 2018

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Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor

21 January 2018

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De novo mutations in the CRX homeobox gene associated with Leber congenital amaurosis

21 January 2018

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Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration

21 January 2018

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A range of clinical phenotypes associated with mutations in CRX, a photoreceptor transcription-factor gene

21 January 2018

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Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

21 January 2018

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Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3

21 January 2018

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Sp3 and Sp4 can repress transcription by competing with Sp1 for the core cis-elements on the human ADH5/FDH minimal promoter

21 January 2018

1 reference

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Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy

21 January 2018

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The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

21 January 2018

1 reference

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The rod cGMP-phosphodiesterase beta-subunit promoter is a specific target for Sp4 and is not activated by other Sp proteins or CRX.

21 January 2018

1 reference

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Transcriptional regulation of the cGMP phosphodiesterase beta-subunit gene

21 January 2018

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Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7

21 January 2018

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Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization

21 January 2018

1 reference

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Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function

21 January 2018

1 reference

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Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression

21 January 2018

1 reference

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Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

21 January 2018

1 reference

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Tissue-specific expression of murine Nkx3.1 in the male urogenital system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500957200

21 January 2018

Identifiers

DOI

10.1074/JBC.M500957200

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20 September 2017

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